ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2HE22.PDB
Scoring matrix: 2HE22_mat
Uniprot code: Q15700
Genome source: Homo sapiens
Wild-type ligand: IHETSV
Foldx wt ligand score: 2.44
Foldx random average score for Homo sapiens: 9.685

Available information for Q15700 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7698
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40363
 Total fragments: 18389199
Proteins after random average filtering: 40358
 Total fragments: 10873892
Proteins after disorder filtering: 31873
 Total fragments: 1012938
Proteins after pattern filtering: 24863
 Total fragments: 134182
Proteins after MINT filtering: 1
 Total fragments: 6


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

IHETSV

2.44

-11.44

0.00

Best peptides

MFMTHV

0.00

-13.51

-2.07

         
Interactors      
Q01814

AIDSGI

5.40

-7.74

3.70

SPGSPI

6.29

-7.22

4.22

KNNSAI

7.13

-8.00

3.44

 


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