ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2EU02.PDB
Scoring matrix: 2EU02_mat
Uniprot code: Q03526
Genome source: Mus musculus
Wild-type ligand: ADyEPP
Foldx wt ligand score: 20.56
Foldx random average score for Mus musculus: 26.118

Available information for Q03526 in MINT (Nov 2008):
Nš of interacting proteins: 3
 Proteins belonging to other specie: 1
Nš of interactions described: 4
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 6057
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 38389
 Total fragments: 17582805
Proteins after random average filtering: 38388
 Total fragments: 9078744
Proteins after disorder filtering: 29409
 Total fragments: 1447568
Proteins after pattern filtering: 14864
 Total fragments: 92909
Proteins after MINT filtering: 1
 Total fragments: 10


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

ADyEPP

20.56

0.66

0.00

Best peptides

yyGDGG

0.00

12.52

11.86

         
Interactors      
Q9QUN3

PRRDYA

12.41

5.51

4.85

YEPPPA

12.71

5.11

4.45

DSYEPP

20.18

2.96

2.30

 


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