|
Matrix information:
(Help)
ADAN-name: 2EGK2.PDB
Scoring matrix: 2EGK2_mat
Uniprot code: Q8R4T5
Genome source: Rattus norvegicus
Wild-type ligand: ESQL
Foldx wt ligand score: 3.82
Foldx random average score for Rattus norvegicus: 8.228 Available information for Q8R4T5 in MINT (Nov 2008):
Nš of interacting proteins: 18
Proteins belonging to other specie: 6
Nš of interactions described: 36
Interactions with other species: 6
Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
Total fragments: 4607713
Proteins after random average filtering: 9663
Total fragments: 2778716
Proteins after disorder filtering: 7769
Total fragments: 283523
Proteins after pattern filtering: 6194
Total fragments: 33214
Proteins after MINT filtering: 9
Total fragments: 94
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
ESQL |
3.82
|
-3.14 |
0.00 |
| Best peptides |
PDMM |
0.00
|
-1.25 |
1.89 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P31424 |
PSPI |
1.71
|
-5.18 |
-2.04 |
|
GTPI |
2.60
|
-4.49 |
-1.35 |
|
DMIL |
3.57
|
-2.48 |
0.66 |
| Q62915 |
TAGL |
5.45
|
-0.48 |
2.66 |
|
QSPA |
6.86
|
0.69 |
3.83 |
| P97836 |
PSIL |
2.38
|
-5.12 |
-1.98 |
|
PYLL |
3.06
|
-3.37 |
-0.23 |
|
PSGV |
3.72
|
-3.45 |
-0.31 |
| O88382 |
PLAI |
2.09
|
-4.80 |
-1.66 |
|
PSPL |
2.55
|
-5.52 |
-2.38 |
|
PLQL |
2.86
|
-4.61 |
-1.47 |
| P97838 |
PFCL |
2.70
|
-2.93 |
0.21 |
|
PLSL |
3.17
|
-5.27 |
-2.13 |
|
PSSV |
3.38
|
-3.32 |
-0.18 |
| P63035 |
PFKI |
1.79
|
-3.88 |
-0.74 |
| P31016 |
GFSI |
2.96
|
-3.16 |
-0.02 |
|
PVIV |
3.87
|
-4.32 |
-1.18 |
|
PAHL |
4.10
|
-2.43 |
0.71 |
| Q91Y79 |
PSCV |
3.37
|
-3.31 |
-0.17 |
|
GTPL |
3.44
|
-4.22 |
-1.08 |
|
SIDL |
3.71
|
-2.55 |
0.59 |
| O35431 |
RSDL |
3.78
|
-2.91 |
0.23 |
|
HLPI |
3.92
|
-3.58 |
-0.44 |
|
SLNL |
4.67
|
-3.19 |
-0.05 |
|
