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Matrix information:
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ADAN-name: 2D1X3.PDB
Scoring matrix: 2D1X3_mat
Uniprot code: Q14247
Genome source: Homo sapiens
Wild-type ligand: KRPPPPPPG
Foldx wt ligand score: 3.38
Foldx random average score for Homo sapiens: 9.290 Available information for Q14247 in MINT (Nov 2008):
Nš of interacting proteins: 3
Proteins belonging to other specie: 0
Nš of interactions described: 3
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18250791
Proteins after random average filtering: 40303
Total fragments: 8538051
Proteins after disorder filtering: 29839
Total fragments: 784767
Proteins after pattern filtering: 21627
Total fragments: 297034
Proteins after MINT filtering: 3
Total fragments: 110
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KRPPPPPPG |
3.38
|
-12.99 |
0.00 |
| Best peptides |
YRKPPDNRR |
0.00
|
-11.41 |
1.58 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13153 |
KPPAPPMRN |
4.33
|
-12.24 |
0.75 |
|
SKPLPPNPE |
5.75
|
-10.03 |
2.96 |
|
QDKPPAPPM |
6.52
|
-10.45 |
2.54 |
| O00401 |
RRQAPPPPP |
3.67
|
-12.17 |
0.82 |
|
RRDPPNGPN |
4.52
|
-11.06 |
1.93 |
|
VPPPPPNRM |
4.99
|
-11.82 |
1.17 |
| Q13177 |
KPPAPPVRM |
4.78
|
-10.98 |
2.01 |
|
LKPLPSVPE |
5.61
|
-10.46 |
2.53 |
|
EDKPPAPPV |
7.14
|
-9.14 |
3.85 |
|
