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Matrix information:
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ADAN-name: 2D1X2.PDB
Scoring matrix: 2D1X2_mat
Uniprot code: Q14247
Genome source: Homo sapiens
Wild-type ligand: KRPPPPPPG
Foldx wt ligand score: 6.17
Foldx random average score for Homo sapiens: 8.998 Available information for Q14247 in MINT (Nov 2008):
Nš of interacting proteins: 3
Proteins belonging to other specie: 0
Nš of interactions described: 3
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18250791
Proteins after random average filtering: 40299
Total fragments: 8740078
Proteins after disorder filtering: 29306
Total fragments: 701085
Proteins after pattern filtering: 21139
Total fragments: 241968
Proteins after MINT filtering: 3
Total fragments: 87
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KRPPPPPPG |
6.17
|
-11.52 |
0.00 |
| Best peptides |
RKRKHPKRR |
0.00
|
-10.46 |
1.06 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13153 |
DKPPAPPMR |
3.77
|
-11.89 |
-0.37 |
|
KPPAPPMRN |
5.68
|
-9.44 |
2.08 |
|
SKPLPPNPE |
6.33
|
-7.95 |
3.57 |
| O00401 |
VPPPPPNRM |
4.70
|
-10.50 |
1.02 |
|
PPPPPPSRG |
4.85
|
-9.83 |
1.69 |
|
GPPPPPARG |
4.87
|
-10.26 |
1.26 |
| Q13177 |
KPPAPPVRM |
4.53
|
-10.99 |
0.53 |
|
DKPPAPPVR |
5.13
|
-10.18 |
1.34 |
|
SLKPLPSVP |
6.79
|
-7.35 |
4.17 |
|
