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Matrix information:
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ADAN-name: 2D0N2.PDB
Scoring matrix: 2D0N2_mat
Uniprot code: O89100
Genome source: Mus musculus
Wild-type ligand: PSIDRSTKP
Foldx wt ligand score: 6.15
Foldx random average score for Mus musculus: 15.651 Available information for O89100 in MINT (Nov 2008):
Nš of interacting proteins: 14
Proteins belonging to other specie: 8
Nš of interactions described: 28
Interactions with other species: 14
Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44445
Total fragments: 20419696
Proteins after random average filtering: 44442
Total fragments: 9233651
Proteins after disorder filtering: 31508
Total fragments: 606589
Proteins after pattern filtering: 20529
Total fragments: 130328
Proteins after MINT filtering: 6
Total fragments: 113
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PSIDRSTKP |
6.15
|
-12.18 |
0.00 |
| Best peptides |
MGRPRHVRR |
0.00
|
-10.79 |
1.39 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9QUN3 |
KGPPSVPRR |
8.73
|
-10.78 |
1.40 |
|
PQVPPKPKD |
11.61
|
-6.76 |
5.42 |
|
PVFPPTQKP |
11.65
|
-7.56 |
4.62 |
| P70218 |
GPPPRTPRP |
9.19
|
-12.81 |
-0.63 |
|
PSLWNPAAP |
13.03
|
-5.37 |
6.81 |
|
PPRTPRPGP |
13.57
|
-6.43 |
5.75 |
| Q80U87 |
PSKLPTQMP |
11.61
|
-8.33 |
3.85 |
|
PSTPPTHKV |
12.39
|
-5.85 |
6.33 |
|
PEMAPSSAP |
14.07
|
-4.41 |
7.77 |
| Q9Z1S8 |
APPPRPPKP |
10.78
|
-9.35 |
2.83 |
|
SAIAPPPRP |
10.93
|
-8.86 |
3.32 |
|
GSPSPHRKP |
12.21
|
-5.90 |
6.28 |
| O35601 |
DSKPRFPRH |
8.56
|
-10.32 |
1.86 |
|
FLKPVSPKP |
11.35
|
-7.02 |
5.16 |
|
DLKTPGPKP |
11.77
|
-7.17 |
5.01 |
| Q9QYY0 |
IPPPRPPKP |
10.26
|
-10.18 |
2.00 |
|
SSPKTPPRR |
10.59
|
-9.75 |
2.43 |
|
KTPPRRPVP |
11.41
|
-9.89 |
2.29 |
|
