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Matrix information:
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ADAN-name: 2BZ83.PDB
Scoring matrix: 2BZ83_mat
Uniprot code: Q96B97
Genome source: Homo sapiens
Wild-type ligand: PARPPKPRPRR
Foldx wt ligand score: 7.15
Foldx random average score for Homo sapiens: 13.034 Available information for Q96B97 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 5
Nš of interactions described: 78
Interactions with other species: 18
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18170060
Proteins after random average filtering: 40290
Total fragments: 8528519
Proteins after disorder filtering: 27403
Total fragments: 444800
Proteins after pattern filtering: 19815
Total fragments: 172786
Proteins after MINT filtering: 10
Total fragments: 325
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PARPPKPRPRR |
7.15
|
-12.97 |
0.00 |
| Best peptides |
RMRKRIDLRAK |
0.00
|
-14.67 |
-1.70 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
PSRDPHYQDPH |
10.44
|
-6.67 |
6.30 |
|
PKRPAGSVQNP |
11.07
|
-8.77 |
4.20 |
|
CPTNGPKIPSI |
11.82
|
-7.63 |
5.34 |
| Q99963 |
IPMDQPCCRGL |
8.57
|
-11.01 |
1.96 |
|
GSNIPMDQPCC |
11.77
|
-7.31 |
5.66 |
| P22681 |
PLPVPPTLRDL |
6.53
|
-11.92 |
1.05 |
|
QRRPLPCTPGD |
7.48
|
-10.15 |
2.82 |
|
PQRRPLPCTPG |
8.14
|
-9.18 |
3.79 |
| Q99961 |
RSMPPLDQPSC |
8.80
|
-10.55 |
2.42 |
|
KPREPFDLGEP |
9.38
|
-8.90 |
4.07 |
|
PSRSMPPLDQP |
10.01
|
-10.68 |
2.29 |
| Q8WUM4 |
APRTMPPTKPQ |
7.35
|
-12.56 |
0.41 |
|
PARPPPPVLPA |
8.29
|
-11.34 |
1.63 |
|
ARPPPPVLPAN |
9.31
|
-13.01 |
-0.04 |
| O43150 |
VHPPLPPLRVT |
7.57
|
-11.68 |
1.29 |
|
QIRPPPLPPQP |
8.41
|
-12.34 |
0.63 |
|
PSRLPQKKPAP |
9.45
|
-10.61 |
2.36 |
| Q13191 |
PARPPKPRPRR |
7.15
|
-12.45 |
0.52 |
|
PLRDPPPPPPE |
8.10
|
-11.33 |
1.64 |
|
PGSSPLAQRRK |
8.41
|
-10.76 |
2.21 |
| P78314 |
SKRDPLCPRRA |
4.96
|
-13.63 |
-0.66 |
|
CPRVPATPRRM |
7.21
|
-12.34 |
0.63 |
|
TMPTAPGLRKP |
7.67
|
-11.63 |
1.34 |
| Q9ULH1 |
KKRPPPPPPGH |
7.65
|
-12.99 |
-0.02 |
|
DLPPKPQMKDL |
8.56
|
-9.51 |
3.46 |
|
QMKDLPPKPQL |
8.75
|
-9.54 |
3.43 |
| O43597 |
TVVPRPGLKPA |
8.87
|
-10.27 |
2.70 |
|
VPRPGLKPAPR |
9.68
|
-10.69 |
2.28 |
|
ECTYPRPLPSD |
10.67
|
-8.07 |
4.90 |
|
