ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2BZ82.PDB
Scoring matrix: 2BZ82_mat
Uniprot code: Q96B97
Genome source: Homo sapiens
Wild-type ligand: PARPPKPRPRR
Foldx wt ligand score: 3.49
Foldx random average score for Homo sapiens: 8.897

Available information for Q96B97 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 5
Nš of interactions described: 78
 Interactions with other species: 18

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
 Total fragments: 18170060
Proteins after random average filtering: 40286
 Total fragments: 8630767
Proteins after disorder filtering: 28809
 Total fragments: 597132
Proteins after pattern filtering: 21070
 Total fragments: 242982
Proteins after MINT filtering: 10
 Total fragments: 400


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

PARPPKPRPRR

3.49

-11.14

0.00

Best peptides

RMRHRWPRRRI

0.00

-12.89

-1.75

         
Interactors      
P00533

NQPLNPAPSRD

4.84

-9.79

1.35

PVYHNQPLNPA

6.20

-6.45

4.69

VPKRPAGSVQN

7.00

-7.65

3.49

Q99963

NIPMDQPCCRG

4.08

-9.19

1.95

PMDQPCCRGLY

6.25

-6.75

4.39

SNIPMDQPCCR

8.52

-5.89

5.25

P22681

QASLPPVPPRL

2.86

-12.28

-1.14

PERPPKPFPRR

3.74

-11.17

-0.03

MEPRPDVPRLG

3.77

-11.30

-0.16

Q99961

SDKPIRTPSRS

5.11

-10.31

0.83

KPKPREPFDLG

5.72

-7.61

3.53

REYKPKPREPF

6.19

-6.36

4.78

Q8WUM4

APTPPTPAPRT

4.11

-10.20

0.94

QYNMPYPPVYH

4.41

-10.61

0.53

PPPPVLPANRA

4.77

-9.94

1.20

O43150

PPLPPQPPSRL

3.63

-11.67

-0.53

VLQPPAPMPRK

3.69

-11.99

-0.85

AVHPPLPPLRV

3.71

-11.55

-0.41

Q13191

SGQVPLPPARR

3.39

-10.60

0.54

SLPPPPPPARH

3.44

-12.55

-1.41

PARPPKPRPRR

3.49

-11.29

-0.15

P78314

PCPRVPATPRR

4.03

-12.35

-1.21

CPRVPATPRRM

4.20

-10.15

0.99

SKRDPLCPRRA

4.50

-9.87

1.27

Q9ULH1

LPETPVPLPRK

3.69

-10.52

0.62

SKKRPPPPPPG

4.65

-11.53

-0.39

KRPPPPPPGHK

5.45

-8.82

2.32

O43597

PRPGLKPAPRP

6.37

-10.45

0.69

LKPAPRPSTQH

6.50

-6.18

4.96

GPTVVPRPGLK

6.70

-6.58

4.56

 


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