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Matrix information:
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ADAN-name: 2BTP2.PDB
Scoring matrix: 2BTP2_mat
Uniprot code: P27348
Genome source: Homo sapiens
Wild-type ligand: RQRsAP
Foldx wt ligand score: 6.76
Foldx random average score for Homo sapiens: 11.741 Available information for P27348 in MINT (Nov 2008):
Nš of interacting proteins: 33
Proteins belonging to other specie: 1
Nš of interactions described: 50
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18372035
Proteins after random average filtering: 40310
Total fragments: 9860475
Proteins after disorder filtering: 31378
Total fragments: 877776
Proteins after pattern filtering: 2585
Total fragments: 3084
Proteins after MINT filtering: 4
Total fragments: 4
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RQRsAP |
6.76
|
-11.36 |
0.00 |
| Best peptides |
yMMsyP |
0.00
|
-11.32 |
0.04 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P15056 |
RSSSAP |
11.29
|
-6.29 |
5.07 |
| P49815 |
RSMSGG |
11.06
|
-6.20 |
5.16 |
| P78314 |
RRMSDP |
7.55
|
-10.51 |
0.85 |
| Q6PKG0 |
RHSSNP |
10.26
|
-8.53 |
2.83 |
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