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Matrix information:
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ADAN-name: 2BR92.PDB
Scoring matrix: 2BR92_mat
Uniprot code: P62258
Genome source: Homo sapiens
Wild-type ligand: RQRsAP
Foldx wt ligand score: 8.04
Foldx random average score for Homo sapiens: 11.354 Available information for P62258 in MINT (Nov 2008):
Nš of interacting proteins: 23
Proteins belonging to other specie: 2
Nš of interactions described: 39
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18372025
Proteins after random average filtering: 40309
Total fragments: 9221581
Proteins after disorder filtering: 31232
Total fragments: 730457
Proteins after pattern filtering: 1553
Total fragments: 1805
Proteins after MINT filtering: 2
Total fragments: 3
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RQRsAP |
8.04
|
-11.99 |
0.00 |
| Best peptides |
yMYEMy |
0.00
|
-12.87 |
-0.88 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P30304 |
RDSSEP |
11.10
|
-7.24 |
4.75 |
| Q9Y2U5 |
RDRSSP |
9.80
|
-7.27 |
4.72 |
|
RAQSYP |
9.92
|
-9.22 |
2.77 |
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