ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2AWW2.PDB
Scoring matrix: 2AWW2_mat
Uniprot code: Q811D0
Genome source: Mus musculus
Wild-type ligand: ATGL
Foldx wt ligand score: 4.7
Foldx random average score for Mus musculus: 6.488

Available information for Q811D0 in MINT (Nov 2008):
Nš of interacting proteins: 5
 Proteins belonging to other specie: 0
Nš of interactions described: 10
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 5625
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 38821
 Total fragments: 17873592
Proteins after random average filtering: 38820
 Total fragments: 9143291
Proteins after disorder filtering: 29800
 Total fragments: 763919
Proteins after pattern filtering: 23497
 Total fragments: 126172
Proteins after MINT filtering: 5
 Total fragments: 25


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

ATGL

4.70

-6.81

0.00

Best peptides

PMMI

0.00

-6.64

0.17

         
Interactors      
P35438

NTNI

3.48

-5.38

1.43

PTPV

3.85

-6.61

0.20

Q61090

PFTA

4.19

-4.75

2.06

EICV

4.62

-4.60

2.21

GISV

4.69

-5.14

1.67

Q61088

KTPI

3.68

-6.13

0.68

EVPL

4.35

-6.82

-0.01

Q810U4

PFDL

2.22

-8.16

-1.35

PTFL

2.49

-8.73

-1.92

HFDI

2.55

-4.56

2.25

O70421

PSLL

3.40

-7.29

-0.48

ELCV

3.73

-6.34

0.47

GISI

3.88

-5.59

1.22

 


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