ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2AK53.PDB
Scoring matrix: 2AK53_mat
Uniprot code: O55043
Genome source: Rattus norvegicus
Wild-type ligand: RPPKPRPR
Foldx wt ligand score: 1.91
Foldx random average score for Rattus norvegicus: 8.845

Available information for O55043 in MINT (Nov 2008):
Nš of interacting proteins: 5
 Proteins belonging to other specie: 0
Nš of interactions described: 6
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11953
 Total fragments: 5568250
Proteins after random average filtering: 11953
 Total fragments: 2580861
Proteins after disorder filtering: 8862
 Total fragments: 142467
Proteins after pattern filtering: 5456
 Total fragments: 30670
Proteins after MINT filtering: 5
 Total fragments: 146


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RPPKPRPR

1.91

-12.19

0.00

Best peptides

RRLLGQFD

0.00

-12.58

-0.39

         
Interactors      
P35465

KPLPPNPE

6.00

-9.26

2.93

HGSKPLPP

6.12

-9.07

3.12

LPPNPEEK

7.25

-7.14

5.05

Q9QX74

RMQPSKFP

3.73

-10.13

2.06

RKKAPPPP

4.22

-11.49

0.70

KEILPTPP

5.47

-9.06

3.13

Q9Z272

RQPPGPVP

5.70

-9.14

3.05

VPVPSLPS

7.88

-7.04

5.15

Q9JLU4

RGPLASPA

3.81

-10.98

1.21

RPGTPELA

3.99

-10.28

1.91

RRRAPPPP

4.06

-10.46

1.73

Q9WV48

RQPRGRPS

1.77

-11.82

0.37

RRVLPTSP

3.39

-11.18

1.01

RPPSPRYD

3.56

-11.39

0.80

 


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