ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2AK52.PDB
Scoring matrix: 2AK52_mat
Uniprot code: O55043
Genome source: Rattus norvegicus
Wild-type ligand: RPPKPRPR
Foldx wt ligand score: 1.85
Foldx random average score for Rattus norvegicus: 7.469

Available information for O55043 in MINT (Nov 2008):
Nš of interacting proteins: 5
 Proteins belonging to other specie: 0
Nš of interactions described: 6
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11953
 Total fragments: 5568250
Proteins after random average filtering: 11951
 Total fragments: 2618659
Proteins after disorder filtering: 8847
 Total fragments: 209221
Proteins after pattern filtering: 6133
 Total fragments: 69436
Proteins after MINT filtering: 5
 Total fragments: 468


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RPPKPRPR

1.85

-11.29

0.00

Best peptides

DMPRPPNR

0.00

-12.70

-1.41

         
Interactors      
P35465

KPPAPPMR

1.70

-11.76

-0.47

PPPVIAPR

2.87

-10.55

0.74

DKPPAPPM

3.45

-9.48

1.81

Q9QX74

KAPPPPKR

1.70

-11.79

-0.50

KRPQPPHW

2.81

-9.91

1.38

PTPGAAPR

2.91

-9.55

1.74

Q9Z272

VPSLPSER

4.68

-8.36

2.93

PVPVPSLP

5.21

-7.28

4.01

QPPGPVPV

5.28

-7.34

3.95

Q9JLU4

ERPKRRPR

1.29

-11.43

-0.14

PPPPPPGR

1.58

-11.61

-0.32

RAPPPPKR

1.69

-11.01

0.28

Q9WV48

GTPQPPPR

1.73

-11.53

-0.24

GVPPPSPR

1.87

-10.72

0.57

GPPGPRLR

1.97

-11.61

-0.32

 


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