ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2AIN2.PDB
Scoring matrix: 2AIN2_mat
Uniprot code: P55196
Genome source: Homo sapiens
Wild-type ligand: LFSTEV
Foldx wt ligand score: 4.85
Foldx random average score for Homo sapiens: 10.366

Available information for P55196 in MINT (Nov 2008):
Nš of interacting proteins: 18
 Proteins belonging to other specie: 0
Nš of interactions described: 30
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 16236
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 31825
 Total fragments: 13442455
Proteins after random average filtering: 31821
 Total fragments: 8880004
Proteins after disorder filtering: 25404
 Total fragments: 1383674
Proteins after pattern filtering: 19751
 Total fragments: 109526
Proteins after MINT filtering: 2
 Total fragments: 11


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

LFSTEV

4.85

-2.10

0.00

Best peptides

HMIFMP

0.00

1.22

3.32

         
Interactors      
P12931

GGAFPA

4.35

-1.72

0.38

SKPASA

5.50

-1.43

0.67

RGPSAA

6.20

0.29

2.39

P11274

GAGSSV

5.27

-2.10

0.00

GQSSRV

5.50

-3.29

-1.19

ESKLPA

5.71

-1.35

0.75

 


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