Matrix information:
(Help) ADAN-name: 2AIN2.PDB Scoring matrix: 2AIN2_mat Uniprot code: P55196 Genome source: Homo sapiens Wild-type ligand: LFSTEV Foldx wt ligand score: 4.85 Foldx random average score for Homo sapiens: 10.366 Available information for P55196 in MINT (Nov 2008): Nš of interacting proteins: 18 Proteins belonging to other specie: 0 Nš of interactions described: 30 Interactions with other species: 0
Genome scanning information:
Subcellular location: True Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 16236 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 31825 Total fragments: 13442455 Proteins after random average filtering: 31821 Total fragments: 8880004 Proteins after disorder filtering: 25404 Total fragments: 1383674 Proteins after pattern filtering: 19751 Total fragments: 109526 Proteins after MINT filtering: 2 Total fragments: 11
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
LFSTEV |
4.85
|
-2.10 |
0.00 |
Best peptides |
HMIFMP |
0.00
|
1.22 |
3.32 |
|
|
|
|
|
Interactors |
|
|
|
|
P12931 |
GGAFPA |
4.35
|
-1.72 |
0.38 |
|
SKPASA |
5.50
|
-1.43 |
0.67 |
|
RGPSAA |
6.20
|
0.29 |
2.39 |
P11274 |
GAGSSV |
5.27
|
-2.10 |
0.00 |
|
GQSSRV |
5.50
|
-3.29 |
-1.19 |
|
ESKLPA |
5.71
|
-1.35 |
0.75 |
|