ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1ZUB2.PDB
Scoring matrix: 1ZUB2_mat
Uniprot code: Q9JIR4
Genome source: Rattus norvegicus
Wild-type ligand: EEGIWA
Foldx wt ligand score: 3.67
Foldx random average score for Rattus norvegicus: 20.010

Available information for Q9JIR4 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 10
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
 Total fragments: 4587166
Proteins after random average filtering: 9663
 Total fragments: 2709923
Proteins after disorder filtering: 7619
 Total fragments: 319213
Proteins after pattern filtering: 5341
 Total fragments: 20748
Proteins after MINT filtering: 1
 Total fragments: 3


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

EEGIWA

3.67

0.92

0.00

Best peptides

MHGMEG

0.00

10.55

9.63

         
Interactors      
Q811U3

HENVGA

8.51

4.39

3.47

GVRMTA

14.10

3.57

2.65

KSTMTL

16.61

5.10

4.18

 


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