ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1ZFP2.PDB
Scoring matrix: 1ZFP2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: EyINQ
Foldx wt ligand score: 2.92
Foldx random average score for Homo sapiens: 15.606

Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
 Proteins belonging to other specie: 6
Nš of interactions described: 157
 Interactions with other species: 28

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
 Total fragments: 13676831
Proteins after random average filtering: 32226
 Total fragments: 8089344
Proteins after disorder filtering: 25764
 Total fragments: 841111
Proteins after pattern filtering: 11047
 Total fragments: 41059
Proteins after MINT filtering: 8
 Total fragments: 38


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

EyINQ

2.92

-16.18

0.00

Best peptides

WyDNM

0.00

-15.02

1.16

         
Interactors      
P27986

NGYNE

11.09

-6.00

10.18

YNETT

12.65

-5.71

10.47

Q07889

SYPLK

13.99

-5.92

10.26

KKYSY

14.17

-3.56

12.62

YSYPL

15.03

-3.22

12.96

Q9UKW4

RNYSG

15.02

-3.36

12.82

Q9UQC2

VYIPM

13.18

-6.11

10.07

GFYSL

13.63

-6.27

9.91

NYVPM

13.67

-5.60

10.58

Q6S383

RYASG

14.29

-5.03

11.15

SPYSV

14.37

-3.29

12.89

YSDPS

14.50

-2.71

13.47

Q13905

QYDNI

8.13

-8.25

7.93

SQYDN

13.30

-3.21

12.97

YDNIS

15.48

-3.05

13.13

Q13480

SLYNL

9.27

-8.74

7.44

YVFNT

10.64

-7.71

8.47

PYQLI

10.95

-8.22

7.96

P58107

YPDPY

12.24

-3.70

12.48

YRDPA

14.36

-3.01

13.17

 


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