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Matrix information:
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ADAN-name: 1YWO2.PDB
Scoring matrix: 1YWO2_mat
Uniprot code: P10686
Genome source: Rattus norvegicus
Wild-type ligand: QPPVPPQRPM
Foldx wt ligand score: 3.24
Foldx random average score for Rattus norvegicus: 8.771 Available information for P10686 in MINT (Nov 2008):
Nš of interacting proteins: 3
Proteins belonging to other specie: 1
Nš of interactions described: 12
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11953
Total fragments: 5543700
Proteins after random average filtering: 11946
Total fragments: 2535640
Proteins after disorder filtering: 8628
Total fragments: 186470
Proteins after pattern filtering: 6100
Total fragments: 74086
Proteins after MINT filtering: 2
Total fragments: 129
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
QPPVPPQRPM |
3.24
|
-13.42 |
0.00 |
| Best peptides |
IRPWPFHRRA |
0.00
|
-12.69 |
0.73 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q8CGU4 |
PAPASPARPV |
4.17
|
-10.77 |
2.65 |
|
PRDPGSPRGA |
4.59
|
-10.90 |
2.52 |
|
PLPGPQGLSS |
4.70
|
-9.86 |
3.56 |
| Q63537 |
GKVLPPRRLP |
2.00
|
-13.80 |
-0.38 |
|
ASPGPERRPP |
3.41
|
-12.12 |
1.30 |
|
SSKTPPQRPA |
4.15
|
-12.03 |
1.39 |
|
