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Matrix information:
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ADAN-name: 1YVL2.PDB
Scoring matrix: 1YVL2_mat
Uniprot code: P42224
Genome source: Homo sapiens
Wild-type ligand: yDKPH
Foldx wt ligand score: 3.36
Foldx random average score for Homo sapiens: 8.216 Available information for P42224 in MINT (Nov 2008):
Nš of interacting proteins: 21
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 9
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 4117
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 43944
Total fragments: 20549440
Proteins after random average filtering: 43941
Total fragments: 10480178
Proteins after disorder filtering: 35336
Total fragments: 1227198
Proteins after pattern filtering: 17599
Total fragments: 82917
Proteins after MINT filtering: 10
Total fragments: 54
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yDKPH |
3.36
|
-10.22 |
0.00 |
| Best peptides |
yDLGR |
0.00
|
-1.76 |
8.46 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P63244 |
YLNTV |
6.77
|
-1.40 |
8.82 |
| P19438 |
YIHPQ |
6.52
|
-3.83 |
6.39 |
|
QGKYI |
6.76
|
-1.96 |
8.26 |
|
YNDCP |
7.37
|
-2.75 |
7.47 |
| O75925 |
YDLQG |
4.14
|
-5.59 |
4.63 |
|
YDGHP |
6.00
|
-3.37 |
6.85 |
|
GYLPP |
6.02
|
-2.48 |
7.74 |
| Q8N6P7 |
YGVCM |
6.76
|
-3.20 |
7.02 |
|
LSYAP |
7.12
|
-2.15 |
8.07 |
|
SYAPQ |
7.77
|
-0.35 |
9.87 |
| P04626 |
DNLYY |
5.33
|
-5.06 |
5.16 |
|
YVAPL |
6.09
|
-3.78 |
6.44 |
|
YLTPQ |
6.61
|
-3.28 |
6.94 |
| Q92793 |
GDDYI |
6.38
|
-1.66 |
8.56 |
|
DDYIF |
6.50
|
-5.23 |
4.99 |
|
YIFHC |
6.98
|
-2.99 |
7.23 |
| P35368 |
GYLGR |
4.10
|
-7.11 |
3.11 |
|
YLGRG |
7.40
|
-2.36 |
7.86 |
| P29597 |
YRCGP |
6.17
|
-3.90 |
6.32 |
|
PAVYR |
6.17
|
-4.58 |
5.64 |
|
SLYCY |
6.31
|
-4.30 |
5.92 |
| P48551 |
GGYTM |
6.61
|
-2.96 |
7.26 |
|
YTMHG |
7.05
|
-4.48 |
5.74 |
|
YDDES |
7.66
|
-0.94 |
9.28 |
| P38398 |
DRWYM |
6.32
|
-4.06 |
6.16 |
|
QNPYR |
6.61
|
-5.34 |
4.88 |
|
NPYRI |
7.09
|
-3.23 |
6.99 |
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