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Matrix information:
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ADAN-name: 1X273.PDB
Scoring matrix: 1X273_mat
Uniprot code: P06239
Genome source: Homo sapiens
Wild-type ligand: DyDYV
Foldx wt ligand score: 3.94
Foldx random average score for Homo sapiens: 7.687 Available information for P06239 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 22
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7698
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40363
Total fragments: 18429920
Proteins after random average filtering: 40353
Total fragments: 9086312
Proteins after disorder filtering: 31691
Total fragments: 1210329
Proteins after pattern filtering: 14822
Total fragments: 62224
Proteins after MINT filtering: 10
Total fragments: 50
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
DyDYV |
3.94
|
-6.18 |
0.00 |
| Best peptides |
yEDsI |
0.00
|
-6.60 |
-0.42 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P20963 |
DGLYQ |
7.57
|
-1.85 |
4.33 |
| P04150 |
GYSSP |
5.69
|
-2.51 |
3.67 |
| P27986 |
GYNET |
6.10
|
-3.02 |
3.16 |
|
YNETT |
7.15
|
-0.88 |
5.30 |
| P22681 |
YDDDD |
4.44
|
-7.47 |
-1.29 |
|
DTEYM |
4.57
|
-3.23 |
2.95 |
|
GYDVP |
4.71
|
-5.01 |
1.17 |
| Q13283 |
SYVHG |
7.52
|
-1.70 |
4.48 |
| Q13444 |
YCEEG |
6.27
|
-3.30 |
2.88 |
|
SYVSC |
7.47
|
-1.15 |
5.03 |
|
YVSCT |
7.54
|
-0.37 |
5.81 |
| Q13094 |
DYESP |
4.22
|
-5.74 |
0.44 |
|
DYEPP |
4.25
|
-6.38 |
-0.20 |
|
YEPPP |
4.75
|
-2.04 |
4.14 |
| Q12959 |
GYAPP |
5.52
|
-3.76 |
2.42 |
|
YMNDG |
5.85
|
-4.79 |
1.39 |
|
MYMND |
6.53
|
-4.01 |
2.17 |
| P43405 |
SYSFP |
6.33
|
-2.07 |
4.11 |
|
YDVVN |
7.44
|
-3.92 |
2.26 |
| P43403 |
VYESP |
5.23
|
-4.19 |
1.99 |
|
YESPY |
5.50
|
-0.86 |
5.32 |
|
YTPEP |
6.41
|
-1.28 |
4.90 |
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