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Matrix information:
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ADAN-name: 1WA72.PDB
Scoring matrix: 1WA72_mat
Uniprot code: P07948
Genome source: Homo sapiens
Wild-type ligand: GMPTPPLPPRPANLGER
Foldx wt ligand score: 16.24
Foldx random average score for Homo sapiens: 42.735 Available information for P07948 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 7
Nš of interactions described: 31
Interactions with other species: 15
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48060
Total fragments: 21767800
Proteins after random average filtering: 47995
Total fragments: 9646494
Proteins after disorder filtering: 29529
Total fragments: 897475
Proteins after pattern filtering: 21433
Total fragments: 351238
Proteins after MINT filtering: 10
Total fragments: 226
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
GMPTPPLPPRPANLGER |
16.24
|
5.38 |
0.00 |
| Best peptides |
DMENIPPMGGPGSMGGG |
0.00
|
18.23 |
12.85 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P22681 |
DPFDPRGSGSLLRQGAE |
14.03
|
7.09 |
1.71 |
|
PLPVPKLPPGEQCEGEE |
15.12
|
6.68 |
1.30 |
|
PSRDKLPPVPSSRLGDS |
16.56
|
3.54 |
-1.84 |
| Q07666 |
SRQPPLPHRSRGGGGGS |
11.71
|
2.53 |
-2.85 |
|
RGRGAAPPPPPVPRGRG |
12.89
|
1.67 |
-3.71 |
|
RGAAPPPPPVPRGRGVG |
15.04
|
7.31 |
1.93 |
| P14317 |
ISSEAWPPVGTPPSSES |
21.64
|
12.98 |
7.60 |
|
SEAWPPVGTPPSSESEP |
32.96
|
16.91 |
11.53 |
|
KISSEAWPPVGTPPSSE |
41.59
|
23.13 |
17.75 |
| Q13444 |
SERPGPPQRALLARGTK |
12.98
|
5.69 |
0.31 |
|
RKPLPADPQGRCPSGDL |
14.36
|
7.04 |
1.66 |
|
KPPPPRKPLPADPQGRC |
20.57
|
2.89 |
-2.49 |
| P29353 |
SHLGATLPVGQPVGGDP |
12.13
|
6.29 |
0.91 |
|
NAQTPSHLGATLPVGQP |
15.57
|
8.32 |
2.94 |
|
ARPTAPNAQTPSHLGAT |
17.97
|
5.64 |
0.26 |
| P43405 |
TQGNVNFGGRPQLPGSH |
25.46
|
6.24 |
0.86 |
|
QGNVNFGGRPQLPGSHP |
30.82
|
17.39 |
12.01 |
|
NFGGRPQLPGSHPATWS |
31.32
|
21.29 |
15.91 |
| Q05397 |
PPKKPPRPGAPGHLGSL |
12.51
|
8.27 |
2.89 |
|
KPSRPGYPSPRSSEGFY |
20.84
|
4.16 |
-1.22 |
|
RPGAPGHLGSLASLSSP |
21.86
|
17.20 |
11.82 |
| Q99759 |
IYQPPEPRSRHLSVSSQ |
27.76
|
18.19 |
12.81 |
|
NTIYQPPEPRSRHLSVS |
29.00
|
19.28 |
13.90 |
|
YQPPEPRSRHLSVSSQN |
31.32
|
16.22 |
10.84 |
| Q13177 |
PAPPVRMSSTIFSTGGK |
19.10
|
4.71 |
-0.67 |
|
KPPAPPVRMSSTIFSTG |
28.58
|
17.39 |
12.01 |
|
PPAPPVRMSSTIFSTGG |
33.76
|
22.86 |
17.48 |
| Q15642 |
GKKNKPRPPPLSPLGGP |
16.76
|
2.29 |
-3.09 |
|
DPPASAPPDSSSNSASQ |
17.47
|
11.27 |
5.89 |
|
RPPPLSPLGGPVPSALP |
20.52
|
8.52 |
3.14 |
|
