ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1W9E2.PDB
Scoring matrix: 1W9E2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: NEFYF
Foldx wt ligand score: 4.57
Foldx random average score for Homo sapiens: 9.701

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 3688
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 44373
 Total fragments: 20763005
Proteins after random average filtering: 44362
 Total fragments: 10021231
Proteins after disorder filtering: 33819
 Total fragments: 586311
Proteins after pattern filtering: 26240
 Total fragments: 118635
Proteins after MINT filtering: 1
 Total fragments: 5


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

NEFYF

4.57

-13.08

0.00

Best peptides

KIMMF

0.00

-3.66

9.42

         
Interactors      
P30203

PKSKL

7.34

-8.96

4.12

AASQL

8.80

-7.21

5.87

PAFSA

9.23

-6.34

6.74

 


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