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Matrix information:
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ADAN-name: 1W702.PDB
Scoring matrix: 1W702_mat
Uniprot code: Q15080
Genome source: Homo sapiens
Wild-type ligand: KPQPAVPPRPSAD
Foldx wt ligand score: 1.84
Foldx random average score for Homo sapiens: 10.749 Available information for Q15080 in MINT (Nov 2008):
Nš of interacting proteins: 2
Proteins belonging to other specie: 0
Nš of interactions described: 2
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18089793
Proteins after random average filtering: 40279
Total fragments: 8852591
Proteins after disorder filtering: 27749
Total fragments: 515777
Proteins after pattern filtering: 20733
Total fragments: 249108
Proteins after MINT filtering: 2
Total fragments: 18
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPQPAVPPRPSAD |
1.84
|
-14.25 |
0.00 |
| Best peptides |
KEMPRIPPRMHRR |
0.00
|
-15.74 |
-1.49 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P13498 |
EPKPRERPQIGGT |
7.79
|
-10.67 |
3.58 |
|
PKPRERPQIGGTI |
8.82
|
-9.58 |
4.67 |
|
QPPSNPPPRPPAE |
8.92
|
-11.03 |
3.22 |
| P19878 |
PQAAEPPPRPKTP |
6.21
|
-10.72 |
3.53 |
|
PPSSKAPGRPQLS |
7.39
|
-10.10 |
4.15 |
|
SPQSDIPAPPSSK |
8.02
|
-9.76 |
4.49 |
|
