ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1V1T2.PDB
Scoring matrix: 1V1T2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: NEYKV
Foldx wt ligand score: 2.64
Foldx random average score for Homo sapiens: 7.028

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 3688
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 44373
 Total fragments: 20763005
Proteins after random average filtering: 44365
 Total fragments: 11406491
Proteins after disorder filtering: 34936
 Total fragments: 789800
Proteins after pattern filtering: 27144
 Total fragments: 138600
Proteins after MINT filtering: 1
 Total fragments: 5


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

NEYKV

2.64

-11.38

0.00

Best peptides

WMIMV

0.00

-12.32

-0.94

         
Interactors      
P30203

PKSKL

4.78

-8.60

2.78

LPTTI

4.93

-7.59

3.79

TTIPA

5.39

-8.24

3.14

 


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