ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1TZE2.PDB
Scoring matrix: 1TZE2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: KPFyVNV
Foldx wt ligand score: 4.41
Foldx random average score for Homo sapiens: 18.780

Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
 Proteins belonging to other specie: 6
Nš of interactions described: 157
 Interactions with other species: 28

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
 Total fragments: 13612377
Proteins after random average filtering: 32222
 Total fragments: 7197725
Proteins after disorder filtering: 24754
 Total fragments: 595692
Proteins after pattern filtering: 11864
 Total fragments: 66532
Proteins after MINT filtering: 9
 Total fragments: 57


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KPFyVNV

4.41

-16.03

0.00

Best peptides

syDyyNM

0.00

-17.63

-1.60

         
Interactors      
P27986

GYNETTG

16.81

-3.44

12.59

YNETTGE

17.68

-1.72

14.31

Q07889

YKREHTH

15.81

-4.19

11.84

KKYSYPL

17.14

-2.22

13.81

LPPKTYK

17.81

4.94

20.97

Q9UKW4

IRNYSGT

17.49

-3.49

12.54

QVIRNYS

18.56

3.44

19.47

Q07890

LPPKTYK

17.81

4.94

20.97

Q9UQC2

EDNYVPM

14.49

-6.67

9.36

VHGFYSL

14.71

-2.15

13.88

EENYVPM

14.77

-7.46

8.57

Q6S383

YYSPYSV

17.36

-3.50

12.53

GRRYASG

17.74

-2.67

13.36

YSPYSVS

18.00

-3.98

12.05

Q13905

PSQYDNI

12.42

-8.80

7.23

HPSQYDN

15.98

-3.39

12.64

SYERHPS

17.46

-3.38

12.65

Q13480

PYQLINV

10.75

-6.79

9.24

ELYVFNT

13.57

-8.34

7.69

DSSLYNL

13.81

-9.69

6.34

P58107

YRDPATG

16.28

-2.55

13.48

YPDPYGG

18.10

-1.15

14.88

 


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