Matrix information:
(Help) ADAN-name: 1TZE2.PDB Scoring matrix: 1TZE2_mat Uniprot code: P62993 Genome source: Homo sapiens Wild-type ligand: KPFyVNV Foldx wt ligand score: 4.41 Foldx random average score for Homo sapiens: 18.780 Available information for P62993 in MINT (Nov 2008): Nš of interacting proteins: 64 Proteins belonging to other specie: 6 Nš of interactions described: 157 Interactions with other species: 28
Genome scanning information:
Subcellular location: True Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 32230 Total fragments: 13612377 Proteins after random average filtering: 32222 Total fragments: 7197725 Proteins after disorder filtering: 24754 Total fragments: 595692 Proteins after pattern filtering: 11864 Total fragments: 66532 Proteins after MINT filtering: 9 Total fragments: 57
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
KPFyVNV |
4.41
|
-16.03 |
0.00 |
Best peptides |
syDyyNM |
0.00
|
-17.63 |
-1.60 |
|
|
|
|
|
Interactors |
|
|
|
|
P27986 |
GYNETTG |
16.81
|
-3.44 |
12.59 |
|
YNETTGE |
17.68
|
-1.72 |
14.31 |
Q07889 |
YKREHTH |
15.81
|
-4.19 |
11.84 |
|
KKYSYPL |
17.14
|
-2.22 |
13.81 |
|
LPPKTYK |
17.81
|
4.94 |
20.97 |
Q9UKW4 |
IRNYSGT |
17.49
|
-3.49 |
12.54 |
|
QVIRNYS |
18.56
|
3.44 |
19.47 |
Q07890 |
LPPKTYK |
17.81
|
4.94 |
20.97 |
Q9UQC2 |
EDNYVPM |
14.49
|
-6.67 |
9.36 |
|
VHGFYSL |
14.71
|
-2.15 |
13.88 |
|
EENYVPM |
14.77
|
-7.46 |
8.57 |
Q6S383 |
YYSPYSV |
17.36
|
-3.50 |
12.53 |
|
GRRYASG |
17.74
|
-2.67 |
13.36 |
|
YSPYSVS |
18.00
|
-3.98 |
12.05 |
Q13905 |
PSQYDNI |
12.42
|
-8.80 |
7.23 |
|
HPSQYDN |
15.98
|
-3.39 |
12.64 |
|
SYERHPS |
17.46
|
-3.38 |
12.65 |
Q13480 |
PYQLINV |
10.75
|
-6.79 |
9.24 |
|
ELYVFNT |
13.57
|
-8.34 |
7.69 |
|
DSSLYNL |
13.81
|
-9.69 |
6.34 |
P58107 |
YRDPATG |
16.28
|
-2.55 |
13.48 |
|
YPDPYGG |
18.10
|
-1.15 |
14.88 |
|