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Matrix information:
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ADAN-name: 1TP52.PDB
Scoring matrix: 1TP52_mat
Uniprot code: P31016
Genome source: Rattus norvegicus
Wild-type ligand: KKETWV
Foldx wt ligand score: 3.1
Foldx random average score for Rattus norvegicus: 8.511 Available information for P31016 in MINT (Nov 2008):
Nš of interacting proteins: 55
Proteins belonging to other specie: 18
Nš of interactions described: 141
Interactions with other species: 34
Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
Total fragments: 4588057
Proteins after random average filtering: 9663
Total fragments: 2933064
Proteins after disorder filtering: 7563
Total fragments: 214772
Proteins after pattern filtering: 5852
Total fragments: 28684
Proteins after MINT filtering: 28
Total fragments: 265
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KKETWV |
3.10
|
-11.46 |
0.00 |
| Best peptides |
RMMIMV |
0.00
|
-14.38 |
-2.92 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q6IN36 |
QRNLSL |
4.45
|
-10.55 |
0.91 |
|
GGLFQA |
5.19
|
-6.81 |
4.65 |
|
HPISDL |
5.24
|
-10.48 |
0.98 |
| Q8R4T5 |
ETPASV |
5.19
|
-7.71 |
3.75 |
|
GPLLAA |
6.00
|
-7.45 |
4.01 |
|
SAETPA |
6.81
|
-8.35 |
3.11 |
| Q63226 |
NDDYTL |
3.57
|
-10.59 |
0.87 |
|
KTMSSI |
4.55
|
-9.82 |
1.64 |
|
TLGLNL |
4.68
|
-10.19 |
1.27 |
| Q62765 |
PVMVYI |
3.04
|
-13.27 |
-1.81 |
|
PDDVPL |
3.40
|
-10.91 |
0.55 |
|
PLRITV |
3.48
|
-12.19 |
-0.73 |
| P15385 |
GGYSSV |
5.74
|
-8.24 |
3.22 |
|
CSYTDL |
6.45
|
-8.46 |
3.00 |
|
PHCSDL |
6.71
|
-9.05 |
2.41 |
| Q71RJ2 |
RDASPV |
4.71
|
-10.16 |
1.30 |
|
ASPVGV |
5.38
|
-7.66 |
3.80 |
| Q9WV48 |
PLLLQL |
3.19
|
-11.97 |
-0.51 |
|
TRLLSL |
3.59
|
-12.33 |
-0.87 |
|
GRSMSV |
3.77
|
-9.96 |
1.50 |
| Q8K430 |
SPTLSV |
4.56
|
-10.52 |
0.94 |
|
DGSSSL |
6.32
|
-7.70 |
3.76 |
| Q9QX19 |
RGRLPA |
6.71
|
-7.98 |
3.48 |
|
VASSPA |
7.26
|
-5.08 |
6.38 |
| Q00960 |
PLDIGL |
4.20
|
-9.98 |
1.48 |
|
ANKSSV |
4.44
|
-9.72 |
1.74 |
|
GSGYML |
4.64
|
-9.57 |
1.89 |
| Q9JJ40 |
PISAPL |
4.94
|
-10.60 |
0.86 |
|
VKEAPA |
5.94
|
-7.14 |
4.32 |
|
EAPAPI |
6.15
|
-5.53 |
5.93 |
| P11506 |
GDGLQL |
4.49
|
-9.60 |
1.86 |
|
GLQLPA |
5.39
|
-9.24 |
2.22 |
|
DSGINL |
5.61
|
-9.84 |
1.62 |
| P97924 |
PYQFRV |
3.87
|
-9.24 |
2.22 |
|
RKSFDL |
3.99
|
-9.85 |
1.61 |
|
YSSVPV |
4.42
|
-10.04 |
1.42 |
| P30937 |
PATLPL |
5.26
|
-10.42 |
1.04 |
|
NTPATL |
5.95
|
-8.10 |
3.36 |
|
TPGINA |
6.69
|
-8.71 |
2.75 |
| P05696 |
KHKFKI |
5.13
|
-11.48 |
-0.02 |
|
DPYVKL |
5.56
|
-10.75 |
0.71 |
| Q9WUL3 |
QGSYMV |
3.39
|
-9.77 |
1.69 |
|
GKKARL |
3.76
|
-11.80 |
-0.34 |
|
KARLQL |
4.37
|
-7.95 |
3.51 |
| P20595 |
DPQFHL |
4.28
|
-12.21 |
-0.75 |
| Q9QUH6 |
KDLFYV |
1.42
|
-11.89 |
-0.43 |
|
MDMARL |
3.02
|
-10.98 |
0.48 |
|
PPQITI |
4.76
|
-11.45 |
0.01 |
| P70587 |
DKGIFV |
3.79
|
-12.31 |
-0.85 |
|
TPETEV |
4.00
|
-11.97 |
-0.51 |
|
IFVTRV |
4.14
|
-11.79 |
-0.33 |
| Q9Z1T4 |
CLNAPV |
3.97
|
-10.23 |
1.23 |
|
LQDLYI |
4.38
|
-12.04 |
-0.58 |
|
PRSFTL |
4.84
|
-9.91 |
1.55 |
| Q62936 |
YGDWQV |
4.02
|
-10.69 |
0.77 |
|
EPSLSV |
4.27
|
-9.23 |
2.23 |
|
RTKAKL |
4.67
|
-10.57 |
0.89 |
| P97836 |
YLLSPV |
3.70
|
-10.14 |
1.32 |
|
DGDMCL |
4.71
|
-9.03 |
2.43 |
|
HKPYLL |
4.92
|
-11.12 |
0.34 |
| P35439 |
VGNTNI |
5.63
|
-10.65 |
0.81 |
|
FTPTPV |
5.76
|
-8.73 |
2.73 |
| Q63622 |
EYKTSL |
4.52
|
-10.30 |
1.16 |
|
YPHYHL |
5.00
|
-11.06 |
0.40 |
|
GLGFSI |
5.22
|
-9.26 |
2.20 |
| Q62868 |
MDSSSI |
5.82
|
-7.80 |
3.66 |
| P29476 |
PKTIRV |
3.84
|
-12.48 |
-1.02 |
|
VPCILV |
3.98
|
-12.11 |
-0.65 |
|
APSFHL |
4.10
|
-11.64 |
-0.18 |
| Q00959 |
EPSFHL |
4.19
|
-11.22 |
0.24 |
|
SCLSNL |
4.32
|
-10.17 |
1.29 |
|
GNKSSL |
4.85
|
-9.64 |
1.82 |
| Q9WVI4 |
CPLSKL |
5.22
|
-10.89 |
0.57 |
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