ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1SEM2.PDB
Scoring matrix: 1SEM2_mat
Uniprot code: P29355
Genome source: Caenorhabditis elegans
Wild-type ligand: PPPVPPR
Foldx wt ligand score: 2.33
Foldx random average score for Caenorhabditis elegans: 9.020

Available information for P29355 in MINT (Nov 2008):
Nš of interacting proteins: 13
 Proteins belonging to other specie: 0
Nš of interactions described: 14
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Caenorhabditis elegans: 23626
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 524
Total scanned proteins: 23101
 Total fragments: 9992466
Proteins after random average filtering: 23101
 Total fragments: 4710287
Proteins after disorder filtering: 15297
 Total fragments: 418653
Proteins after pattern filtering: 8669
 Total fragments: 89563
Proteins after MINT filtering: 11
 Total fragments: 173


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

PPPVPPR

2.33

-9.56

0.00

Best peptides

RPIRPGR

0.00

-7.30

2.26

         
Interactors      
Q20771

PPSRPFS

3.70

-7.78

1.78

PQSCPGG

5.87

-5.27

4.29

PQQYPPP

6.48

-5.29

4.27

Q21848

PETFPLC

6.34

-5.01

4.55

PNSDPRK

6.56

-4.80

4.76

PNNTPET

7.17

-4.51

5.05

Q20473

PPPLPPR

1.54

-9.41

0.15

APPLPSR

2.00

-7.31

2.25

PPLPPRR

2.63

-8.89

0.67

P91482

PPARPRP

3.62

-8.68

0.88

ARPRPGP

4.11

-7.58

1.98

VPVPPAR

4.54

-6.36

3.20

Q9XVW8

APPLPPK

4.05

-8.01

1.55

PNMAPNR

4.30

-6.24

3.32

QPNMAPN

4.82

-4.70

4.86

Q9N5D3

APPLPPR

1.76

-8.15

1.41

PKLHPRR

3.25

-6.61

2.95

SPLTPSR

3.41

-6.14

3.42

Q93203

PPPLPPR

1.54

-9.41

0.15

PPLPPRS

5.41

-6.54

3.02

RPPAPYD

5.60

-6.14

3.42

Q9XU98

KPTDPPR

2.60

-7.78

1.78

PTDPPRP

7.68

-4.78

4.78

PKPTDPP

8.97

-2.64

6.92

Q23158

RDPPPPV

5.03

-6.94

2.62

MRDPPPP

5.31

-6.44

3.12

PPPPVIR

5.82

-5.02

4.54

Q19019

APPLPPR

1.76

-8.15

1.41

PPPLPPK

3.83

-9.41

0.15

PPLPPRL

4.96

-6.80

2.76

O45539

LPSHPRI

5.87

-6.06

3.50

HPRIPSI

5.98

-6.44

3.12

SLPSHPR

6.71

-3.63

5.93

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER