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Matrix information:
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ADAN-name: 1RQQ2.PDB
Scoring matrix: 1RQQ2_mat
Uniprot code: P06213
Genome source: Homo sapiens
Wild-type ligand: IyETDyyR
Foldx wt ligand score: 1.99
Foldx random average score for Homo sapiens: 14.765 Available information for P06213 in MINT (Nov 2008):
Nš of interacting proteins: 8
Proteins belonging to other specie: 2
Nš of interactions described: 25
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18290270
Proteins after random average filtering: 40304
Total fragments: 10769970
Proteins after disorder filtering: 30737
Total fragments: 1009388
Proteins after pattern filtering: 14763
Total fragments: 87152
Proteins after MINT filtering: 3
Total fragments: 110
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
IyETDyyR |
1.99
|
-12.87 |
0.00 |
| Best peptides |
syEGsyyN |
0.00
|
-9.58 |
3.29 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q14449 |
APTNYGFC |
13.25
|
-2.50 |
10.37 |
|
TNYGFCFK |
13.80
|
-0.22 |
12.65 |
|
GAPTNYGF |
14.61
|
-0.76 |
12.11 |
| Q9Y4H2 |
GDNGDYTE |
8.73
|
-2.68 |
10.19 |
|
ADDGYMPM |
9.90
|
-1.82 |
11.05 |
|
YMTMDRPL |
10.18
|
-5.07 |
7.80 |
| P35568 |
PCTGDYMN |
9.57
|
-2.16 |
10.71 |
|
TDDGYMPM |
9.81
|
-2.11 |
10.76 |
|
DSLGGGYC |
10.39
|
-2.30 |
10.57 |
|
