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Matrix information:
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ADAN-name: 1QG12.PDB
Scoring matrix: 1QG12_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: DDPSyVNVQNLDK
Foldx wt ligand score: 24.03
Foldx random average score for Homo sapiens: 25.072 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13419065
Proteins after random average filtering: 32192
Total fragments: 7118672
Proteins after disorder filtering: 23385
Total fragments: 744869
Proteins after pattern filtering: 11841
Total fragments: 121611
Proteins after MINT filtering: 7
Total fragments: 109
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
DDPSyVNVQNLDK |
24.03
|
2.21 |
0.00 |
| Best peptides |
DDGGGyGGyssps |
0.00
|
10.74 |
8.53 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
NGYNETTGERGDF |
15.94
|
2.07 |
-0.14 |
|
GYNETTGERGDFP |
23.83
|
2.48 |
0.27 |
| Q07889 |
LPRFPKKYSYPLK |
16.95
|
1.36 |
-0.85 |
|
PKLPPKTYKREHT |
19.53
|
1.54 |
-0.67 |
|
KYSYPLKSPGVRP |
20.79
|
0.02 |
-2.19 |
| Q9UKW4 |
VIRNYSGTPPPAL |
19.54
|
3.09 |
0.88 |
|
QVIRNYSGTPPPA |
20.24
|
1.95 |
-0.26 |
| Q9UQC2 |
STDSGDSEENYVP |
14.82
|
3.05 |
0.84 |
|
AHHFDSLGYPSTT |
15.15
|
0.99 |
-1.22 |
|
TDSGDSEENYVPM |
15.56
|
-0.32 |
-2.53 |
| Q6S383 |
YSVSGSGSTAGSR |
11.17
|
2.14 |
-0.07 |
|
GRRYASGSSASLG |
13.24
|
2.08 |
-0.13 |
|
AYSDPSTGEPATY |
14.87
|
2.71 |
0.50 |
| Q13905 |
SHSYGGESPRLSP |
15.56
|
3.20 |
0.99 |
|
GGSHSYGGESPRL |
17.23
|
4.83 |
2.62 |
|
GSHSYGGESPRLS |
17.40
|
2.81 |
0.60 |
| Q13480 |
SYCIPTAGMSPSR |
16.00
|
2.54 |
0.33 |
|
SHDSEENYVPMNP |
16.73
|
1.70 |
-0.51 |
|
RAPSASVDSSLYN |
17.29
|
1.80 |
-0.41 |
|
