ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1Q3P2.PDB
Scoring matrix: 1Q3P2_mat
Uniprot code: Q9WV48
Genome source: Rattus norvegicus
Wild-type ligand: EAQTRL
Foldx wt ligand score: 5.88
Foldx random average score for Rattus norvegicus: 9.772

Available information for Q9WV48 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 3
Nš of interactions described: 33
 Interactions with other species: 10

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
 Total fragments: 4586614
Proteins after random average filtering: 9662
 Total fragments: 2487059
Proteins after disorder filtering: 7404
 Total fragments: 153973
Proteins after pattern filtering: 5445
 Total fragments: 21362
Proteins after MINT filtering: 5
 Total fragments: 30


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

EAQTRL

5.88

-8.29

0.00

Best peptides

GEDDWM

0.00

-6.85

1.44

         
Interactors      
Q63622

EYKTSL

6.76

-6.91

1.38

DPGIFI

7.04

-8.94

-0.65

GLGFSI

7.39

-5.13

3.16

P35439

VGNTNI

7.60

-5.98

2.31

FTPTPV

7.81

-5.38

2.91

P31016

HSPAHL

6.38

-7.37

0.92

GLGFSI

7.39

-5.13

3.16

SPPVIV

8.83

-8.47

-0.18

P97836

DGDMCL

4.24

-5.79

2.50

FDPSIL

5.38

-7.61

0.68

HKPYLL

6.52

-5.96

2.33

O55043

PKPWSL

7.32

-6.12

2.17

WSLSCL

7.36

-6.86

1.43

TPHTTI

9.14

-6.43

1.86

 


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