ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OV33.PDB
Scoring matrix: 1OV33_mat
Uniprot code: P14598
Genome source: Homo sapiens
Wild-type ligand: QPPSNPPPRPP
Foldx wt ligand score: 4.29
Foldx random average score for Homo sapiens: 9.201

Available information for P14598 in MINT (Nov 2008):
Nš of interacting proteins: 11
 Proteins belonging to other specie: 2
Nš of interactions described: 21
 Interactions with other species: 3

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
 Total fragments: 18170335
Proteins after random average filtering: 40290
 Total fragments: 9071989
Proteins after disorder filtering: 29158
 Total fragments: 840345
Proteins after pattern filtering: 21660
 Total fragments: 363929
Proteins after MINT filtering: 5
 Total fragments: 120


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

QPPSNPPPRPP

4.29

-13.86

0.00

Best peptides

GHPHFIMPDIP

0.00

-12.67

1.19

         
Interactors      
P19878

APPSSKAPGRP

3.98

-12.48

1.38

SSPQSDIPAPP

5.53

-10.88

2.98

QPQAAEPPPRP

6.47

-11.31

2.55

Q9C026

CHPPRGPLAKH

4.78

-10.64

3.22

GVRVFPPAMPP

4.88

-10.48

3.38

FPPAMPPPATH

5.17

-12.22

1.64

Q04206

SLVTKDPPHRP

3.45

-12.32

1.54

GPPQAVAPPAP

4.18

-11.42

2.44

APAPLGAPGLP

4.99

-9.37

4.49

P17252

IPMDPNGLSDP

8.80

-8.95

4.91

P13498

KQPPSNPPPRP

4.03

-13.97

-0.11

QPPSNPPPRPP

4.29

-12.33

1.53

AAAAGGPPGGP

5.64

-10.83

3.03

 


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