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Matrix information:
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ADAN-name: 1OPL3.PDB
Scoring matrix: 1OPL3_mat
Uniprot code: P00519
Genome source: Homo sapiens
Wild-type ligand: NKPTVYGVSPN
Foldx wt ligand score: 4.9
Foldx random average score for Homo sapiens: 11.724 Available information for P00519 in MINT (Nov 2008):
Nš of interacting proteins: 29
Proteins belonging to other specie: 2
Nš of interactions described: 54
Interactions with other species: 4
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 4117
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 43944
Total fragments: 20285429
Proteins after random average filtering: 43923
Total fragments: 10181414
Proteins after disorder filtering: 32600
Total fragments: 817324
Proteins after pattern filtering: 23185
Total fragments: 209164
Proteins after MINT filtering: 20
Total fragments: 551
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
NKPTVYGVSPN |
4.90
|
-10.54 |
0.00 |
| Best peptides |
GRPRMPGKWPM |
0.00
|
-11.94 |
-1.40 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P06400 |
TRPPTLSPIPH |
6.44
|
-10.40 |
0.14 |
|
KFPSSPLRIPG |
6.70
|
-9.56 |
0.98 |
|
HIPRSPYKFPS |
7.55
|
-9.23 |
1.31 |
| P00533 |
CDPSCPNGSCW |
8.77
|
-7.84 |
2.70 |
|
GLEGCPTNGPK |
8.83
|
-8.23 |
2.31 |
|
PLNPAPSRDPH |
8.97
|
-7.65 |
2.89 |
| O14746 |
SRPPRPWDTPC |
5.76
|
-10.52 |
0.02 |
|
PKRPRRGAAPE |
6.71
|
-8.98 |
1.56 |
|
PLPKRPRRGAA |
7.45
|
-9.31 |
1.23 |
| O15399 |
EPPLLPGGAPL |
5.13
|
-10.11 |
0.43 |
|
ARCGCPRSHPH |
6.85
|
-8.89 |
1.65 |
|
PLPSPAYPAPG |
7.36
|
-9.47 |
1.07 |
| P22681 |
PLPCTPGDCPS |
5.47
|
-9.88 |
0.66 |
|
NRHSLPFSLPS |
5.92
|
-10.68 |
-0.14 |
|
PRPDVPRLGST |
7.54
|
-8.27 |
2.27 |
| P18031 |
PRPPKRILEPH |
7.89
|
-10.93 |
-0.39 |
|
DLEPPPEHIPP |
10.42
|
-7.07 |
3.47 |
|
LEPPPEHIPPP |
11.36
|
-8.47 |
2.07 |
| Q92558 |
PPPPMHGAGDA |
6.50
|
-8.51 |
2.03 |
|
PSQVIPASEPK |
7.84
|
-7.42 |
3.12 |
|
PGPHVPLMPPS |
8.12
|
-8.06 |
2.48 |
| O15162 |
GVPWMPAPQPP |
6.94
|
-9.78 |
0.76 |
|
PPPPAGHSGPG |
8.40
|
-8.21 |
2.33 |
|
PQPPLNCPPGL |
8.50
|
-7.71 |
2.83 |
| P12931 |
QTPSKPASADG |
9.07
|
-6.82 |
3.72 |
| Q8IZP0 |
PPPPMPQLTPQ |
5.99
|
-10.27 |
0.27 |
|
KPPTVPNDYMT |
7.33
|
-9.11 |
1.43 |
|
SVPPPSGAPPA |
8.22
|
-9.72 |
0.82 |
| Q13671 |
PVPVLPGAVPS |
4.83
|
-10.49 |
0.05 |
|
SLPPMPSLQEV |
6.83
|
-9.14 |
1.40 |
|
KAQRGPAGGPV |
9.62
|
-6.41 |
4.13 |
| P04626 |
PQPPSPREGPL |
7.12
|
-8.99 |
1.55 |
|
GLQSLPTHDPS |
7.34
|
-9.64 |
0.90 |
|
REGPLPAARPA |
8.17
|
-8.56 |
1.98 |
| P21860 |
PIMPTAGTTPD |
8.02
|
-7.66 |
2.88 |
|
LTPVTPLSPPG |
8.94
|
-9.14 |
1.40 |
|
GPGIAPGPEPH |
9.06
|
-5.22 |
5.32 |
| P04637 |
EAPRMPEAAPP |
7.13
|
-9.57 |
0.97 |
|
PSWPLSSSVPS |
7.60
|
-9.15 |
1.39 |
|
PTPAAPAPAPS |
7.92
|
-8.03 |
2.51 |
| O15350 |
PAPVIPSNTDY |
7.54
|
-7.32 |
3.22 |
|
SYGPVLSPMNK |
7.88
|
-8.16 |
2.38 |
|
PNRGGPGGGPD |
8.46
|
-5.90 |
4.64 |
| P15941 |
TPFSIPSHHSD |
9.43
|
-6.05 |
4.49 |
|
DVTSAPDNKPA |
9.70
|
-6.58 |
3.96 |
|
GVTSAPDNRPA |
9.92
|
-7.16 |
3.38 |
| Q9NYB9 |
PAPLVPATVPS |
6.93
|
-9.18 |
1.36 |
|
GTPPLPATSAS |
7.52
|
-9.32 |
1.22 |
|
PTPSPPSVFPA |
8.41
|
-8.68 |
1.86 |
| Q15303 |
CHPCHPNCTQG |
8.66
|
-7.44 |
3.10 |
|
GHSPPPAYTPM |
8.75
|
-7.74 |
2.80 |
|
DRECHPCHPNC |
9.51
|
-6.57 |
3.97 |
| P78527 |
GVWMIPTSDPA |
7.16
|
-9.59 |
0.95 |
|
WMIPTSDPAAN |
9.35
|
-7.48 |
3.06 |
|
TSMSPDYPNPM |
9.65
|
-6.65 |
3.89 |
| Q09472 |
SLPPIVDPDPL |
4.46
|
-11.24 |
-0.70 |
|
GQPGMPQGQPG |
4.49
|
-11.66 |
-1.12 |
|
AQPPLPGPPPT |
4.62
|
-10.75 |
-0.21 |
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