ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OO42.PDB
Scoring matrix: 1OO42_mat
Uniprot code: P23727
Genome source: Bos taurus
Wild-type ligand: SVDyVPML
Foldx wt ligand score: 7.49
Foldx random average score for Bos taurus: 17.547

Available information for P23727 in MINT (Nov 2008):
Nš of interacting proteins: 3
 Proteins belonging to other specie: 2
Nš of interactions described: 5
 Interactions with other species: 3

Genome scanning information:
Subcellular location: True
Proteins in genome Bos taurus: 15166
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3661
Total scanned proteins: 11504
 Total fragments: 4485259
Proteins after random average filtering: 11501
 Total fragments: 2311553
Proteins after disorder filtering: 8293
 Total fragments: 144806
Proteins after pattern filtering: 3686
 Total fragments: 16341
Proteins after MINT filtering: 1
 Total fragments: 5


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

SVDyVPML

7.49

-8.08

0.00

Best peptides

PDDyEMMA

0.00

-10.64

-2.56

         
Interactors      
P17599

NGYMTDLQ

13.41

-3.79

4.29

GYMTDLQR

15.09

0.15

8.23

LPNGYMTD

16.30

0.02

8.10

 


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