ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OBY3.PDB
Scoring matrix: 1OBY3_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: NEFYA
Foldx wt ligand score: 4.37
Foldx random average score for Homo sapiens: 8.710

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 3688
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 44373
 Total fragments: 20763005
Proteins after random average filtering: 44368
 Total fragments: 11775510
Proteins after disorder filtering: 35068
 Total fragments: 874369
Proteins after pattern filtering: 25085
 Total fragments: 101852
Proteins after MINT filtering: 1
 Total fragments: 3


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

NEFYA

4.37

-12.60

0.00

Best peptides

RMIMM

0.00

-14.92

-2.32

         
Interactors      
P30203

TTIPA

6.17

-9.42

3.18

PAFSA

6.81

-8.71

3.89

LPTTI

8.69

-8.03

4.57

 


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