ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OBX2.PDB
Scoring matrix: 1OBX2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: DSVF
Foldx wt ligand score: 4.55
Foldx random average score for Homo sapiens: 6.969

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 3688
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 44373
 Total fragments: 20807378
Proteins after random average filtering: 44368
 Total fragments: 9974565
Proteins after disorder filtering: 34587
 Total fragments: 659437
Proteins after pattern filtering: 25150
 Total fragments: 100188
Proteins after MINT filtering: 1
 Total fragments: 4


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

DSVF

4.55

-8.81

0.00

Best peptides

MWLF

0.00

-0.05

8.76

         
Interactors      
P30203

PVRL

6.06

-8.39

0.42

KSKL

6.12

-7.48

1.33

ASQL

6.62

-6.38

2.43

 


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