ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1N7T2.PDB
Scoring matrix: 1N7T2_mat
Uniprot code: Q96RT1
Genome source: Homo sapiens
Wild-type ligand: TGWETWV
Foldx wt ligand score: 3.02
Foldx random average score for Homo sapiens: 10.186

Available information for Q96RT1 in MINT (Nov 2008):
Nš of interacting proteins: 7
 Proteins belonging to other specie: 1
Nš of interactions described: 17
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 16236
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 31825
 Total fragments: 13411037
Proteins after random average filtering: 31815
 Total fragments: 7314496
Proteins after disorder filtering: 24412
 Total fragments: 549098
Proteins after pattern filtering: 18044
 Total fragments: 78592
Proteins after MINT filtering: 2
 Total fragments: 18


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

TGWETWV

3.02

-7.68

0.00

Best peptides

PGWMDPV

0.00

-4.07

3.61

         
Interactors      
O00192

PDGYSTV

6.11

-3.86

3.82

DDSTLPL

6.23

-4.03

3.65

HREAFPV

6.24

-3.95

3.73

Q99569

RSGMTAV

5.83

-4.11

3.57

GSLRTSL

6.05

-3.57

4.11

PWRSTDV

6.50

-2.60

5.08

 


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