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Matrix information:
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ADAN-name: 1MW42.PDB
Scoring matrix: 1MW42_mat
Uniprot code: Q14451
Genome source: Homo sapiens
Wild-type ligand: PQPEyVNQPD
Foldx wt ligand score: 47.62
Foldx random average score for Homo sapiens: 39.847 Available information for Q14451 in MINT (Nov 2008):
Nš of interacting proteins: 3
Proteins belonging to other specie: 0
Nš of interactions described: 7
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48060
Total fragments: 22103991
Proteins after random average filtering: 48040
Total fragments: 10373607
Proteins after disorder filtering: 35889
Total fragments: 1590514
Proteins after pattern filtering: 19473
Total fragments: 180558
Proteins after MINT filtering: 2
Total fragments: 39
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PQPEyVNQPD |
47.62
|
15.55 |
0.00 |
| Best peptides |
sDGGGGGNyG |
0.00
|
17.13 |
1.58 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P04626 |
SMPNPEGRYT |
20.94
|
8.05 |
-7.50 |
|
EYLTPQGGAA |
21.79
|
7.89 |
-7.66 |
|
SETDGYVAPL |
25.76
|
8.27 |
-7.28 |
| P21860 |
DGGGPGGDYA |
10.29
|
6.28 |
-9.27 |
|
GGGPGGDYAA |
14.71
|
5.84 |
-9.71 |
|
SLLSPSSGYM |
22.64
|
8.49 |
-7.06 |
|
