Matrix information:
(Help) ADAN-name: 1MW42.PDB Scoring matrix: 1MW42_mat Uniprot code: Q14451 Genome source: Homo sapiens Wild-type ligand: PQPEyVNQPD Foldx wt ligand score: 47.62 Foldx random average score for Homo sapiens: 39.847 Available information for Q14451 in MINT (Nov 2008): Nš of interacting proteins: 3 Proteins belonging to other specie: 0 Nš of interactions described: 7 Interactions with other species: 0
Genome scanning information:
Subcellular location: True Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 1 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 48060 Total fragments: 22103991 Proteins after random average filtering: 48040 Total fragments: 10373607 Proteins after disorder filtering: 35889 Total fragments: 1590514 Proteins after pattern filtering: 19473 Total fragments: 180558 Proteins after MINT filtering: 2 Total fragments: 39
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
PQPEyVNQPD |
47.62
|
15.55 |
0.00 |
Best peptides |
sDGGGGGNyG |
0.00
|
17.13 |
1.58 |
|
|
|
|
|
Interactors |
|
|
|
|
P04626 |
SMPNPEGRYT |
20.94
|
8.05 |
-7.50 |
|
EYLTPQGGAA |
21.79
|
7.89 |
-7.66 |
|
SETDGYVAPL |
25.76
|
8.27 |
-7.28 |
P21860 |
DGGGPGGDYA |
10.29
|
6.28 |
-9.27 |
|
GGGPGGDYAA |
14.71
|
5.84 |
-9.71 |
|
SLLSPSSGYM |
22.64
|
8.49 |
-7.06 |
|