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Matrix information:
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ADAN-name: 1MV32.PDB
Scoring matrix: 1MV32_mat
Uniprot code: O00499
Genome source: Homo sapiens
Wild-type ligand: QLRKGPPVPPP
Foldx wt ligand score: 6.96
Foldx random average score for Homo sapiens: 9.103 Available information for O00499 in MINT (Nov 2008):
Nš of interacting proteins: 4
Proteins belonging to other specie: 1
Nš of interactions described: 13
Interactions with other species: 4
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 4117
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 43944
Total fragments: 20285966
Proteins after random average filtering: 43918
Total fragments: 10376792
Proteins after disorder filtering: 32051
Total fragments: 833218
Proteins after pattern filtering: 22507
Total fragments: 221914
Proteins after MINT filtering: 3
Total fragments: 75
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
QLRKGPPVPPP |
6.96
|
-0.12 |
0.00 |
| Best peptides |
KRRHQRMFKPE |
0.00
|
4.02 |
4.14 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| O95219 |
PLGSPDAGLGA |
8.86
|
4.26 |
4.38 |
| Q8TB24 |
SRWAPRRPPPP |
4.99
|
-2.31 |
-2.19 |
|
PRTAKQPPVPP |
5.52
|
-0.65 |
-0.53 |
|
PRDRAPGFPLV |
5.69
|
-3.93 |
-3.81 |
| P39880 |
SRRPGSLPAPP |
5.59
|
-4.43 |
-4.31 |
|
PMSKPTKPSVP |
6.35
|
0.93 |
1.05 |
|
SSSAPRRPSSL |
6.72
|
1.29 |
1.41 |
|
