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Matrix information:
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ADAN-name: 1MV02.PDB
Scoring matrix: 1MV02_mat
Uniprot code: P01106
Genome source: Homo sapiens
Wild-type ligand: LLPTPPLSPSRRSG
Foldx wt ligand score: 9.48
Foldx random average score for Homo sapiens: 19.613 Available information for P01106 in MINT (Nov 2008):
Nš of interacting proteins: 8
Proteins belonging to other specie: 1
Nš of interactions described: 18
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 11708
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 36353
Total fragments: 15852040
Proteins after random average filtering: 36311
Total fragments: 8936421
Proteins after disorder filtering: 26421
Total fragments: 887594
Proteins after pattern filtering: 19195
Total fragments: 328032
Proteins after MINT filtering: 3
Total fragments: 13
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
LLPTPPLSPSRRSG |
9.48
|
0.85 |
0.00 |
| Best peptides |
FLPMPRRNRRRNIG |
0.00
|
1.82 |
0.97 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P40692 |
KLKAPPKPCAGNQG |
11.95
|
0.02 |
-0.83 |
|
DGKLKAPPKPCAGN |
12.63
|
1.60 |
0.75 |
|
SDGKLKAPPKPCAG |
14.04
|
2.69 |
1.84 |
| P38398 |
PGVERSSPSKCPSL |
13.45
|
1.90 |
1.05 |
|
ERSSPSKCPSLDDR |
16.72
|
4.27 |
3.42 |
|
PESDPSEDRAPESA |
17.35
|
4.50 |
3.65 |
| Q13105 |
KADAPREPPPVELK |
13.86
|
-1.85 |
-2.70 |
|
AEPATSPGGNAEAL |
17.10
|
6.32 |
5.47 |
|
