ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1MFL2.PDB
Scoring matrix: 1MFL2_mat
Uniprot code: Q96RT1
Genome source: Homo sapiens
Wild-type ligand: LDVPV
Foldx wt ligand score: 3.52
Foldx random average score for Homo sapiens: 8.336

Available information for Q96RT1 in MINT (Nov 2008):
Nš of interacting proteins: 7
 Proteins belonging to other specie: 1
Nš of interactions described: 17
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 16236
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 31825
 Total fragments: 13474681
Proteins after random average filtering: 31817
 Total fragments: 7297717
Proteins after disorder filtering: 25013
 Total fragments: 569788
Proteins after pattern filtering: 19370
 Total fragments: 93388
Proteins after MINT filtering: 2
 Total fragments: 22


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

LDVPV

3.52

-10.06

0.00

Best peptides

DDFYL

0.00

-11.75

-1.69

         
Interactors      
O00192

SRAYL

3.21

-10.39

-0.33

DDSTL

3.88

-9.82

0.24

GCFTL

4.13

-9.42

0.64

Q99569

PDSWV

2.47

-10.07

-0.01

SPALL

3.83

-9.82

0.24

SPIYI

4.12

-10.49

-0.43

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER