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Matrix information:
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ADAN-name: 1M272.PDB
Scoring matrix: 1M272_mat
Uniprot code: O60880
Genome source: Homo sapiens
Wild-type ligand: KSLTIYAQVQK
Foldx wt ligand score: 11.37
Foldx random average score for Homo sapiens: 15.999 Available information for O60880 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 2
Nš of interactions described: 24
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18170597
Proteins after random average filtering: 40281
Total fragments: 10049551
Proteins after disorder filtering: 26803
Total fragments: 343560
Proteins after pattern filtering: 11692
Total fragments: 46495
Proteins after MINT filtering: 8
Total fragments: 55
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KSLTIYAQVQK |
11.37
|
-15.54 |
0.00 |
| Best peptides |
RNLDMMFMLFN |
0.00
|
-16.28 |
-0.74 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
ISLDNPDYQQD |
10.34
|
-10.78 |
4.76 |
|
PPLMLYNPTTY |
12.11
|
-13.54 |
2.00 |
|
TYQMDVNPEGK |
12.86
|
-10.30 |
5.24 |
| O15117 |
KQLDMGDEVYD |
6.00
|
-14.08 |
1.46 |
|
DIYDGIEEEDA |
9.50
|
-10.30 |
5.24 |
|
PDDDIYDGIEE |
10.34
|
-11.30 |
4.24 |
| Q9BZW8 |
TFPGGGSTIYS |
15.47
|
-8.64 |
6.90 |
| Q14155 |
PAPLTPAYHTL |
14.38
|
-10.41 |
5.13 |
|
AYHTLPHPSHH |
14.44
|
-9.99 |
5.55 |
| P21860 |
NGYVMPDTHLK |
11.20
|
-13.51 |
2.03 |
|
EEEDVNGYVMP |
11.74
|
-9.13 |
6.41 |
|
YMPMNQGNLGE |
11.85
|
-11.28 |
4.26 |
| Q16620 |
GIDDGANPNYP |
15.77
|
-7.39 |
8.15 |
| Q16288 |
THYNNGNYTLI |
12.98
|
-10.26 |
5.28 |
|
YRLFNPSGNDF |
15.11
|
-10.58 |
4.96 |
| P06241 |
PNYNNFHAAGG |
12.08
|
-13.50 |
2.04 |
|
SIPNYNNFHAA |
12.73
|
-11.07 |
4.47 |
|
SLNQSSGYRYG |
14.04
|
-9.98 |
5.56 |
|
