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Matrix information:
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ADAN-name: 1KWA2.PDB
Scoring matrix: 1KWA2_mat
Uniprot code: O14936
Genome source: Homo sapiens
Wild-type ligand: VPSYREF
Foldx wt ligand score: 5.16
Foldx random average score for Homo sapiens: 11.132 Available information for O14936 in MINT (Nov 2008):
Nš of interacting proteins: 13
Proteins belonging to other specie: 2
Nš of interactions described: 22
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 4117
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 43944
Total fragments: 20461382
Proteins after random average filtering: 43932
Total fragments: 10829635
Proteins after disorder filtering: 32931
Total fragments: 576627
Proteins after pattern filtering: 22991
Total fragments: 85460
Proteins after MINT filtering: 8
Total fragments: 34
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPSYREF |
5.16
|
-15.93 |
0.00 |
| Best peptides |
MMFFMDF |
0.00
|
-10.40 |
5.53 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9BZL6 |
PPGGLEL |
7.27
|
-12.09 |
3.84 |
| Q12929 |
PNNILDI |
6.83
|
-18.33 |
-2.40 |
|
APVPVPL |
7.52
|
-14.79 |
1.14 |
|
GEGVLTL |
8.24
|
-13.06 |
2.87 |
| Q9C0A0 |
GPFEISV |
7.53
|
-16.73 |
-0.80 |
|
SKCKSPL |
7.57
|
-14.53 |
1.40 |
|
GPGFARL |
7.86
|
-12.04 |
3.89 |
| Q9Y2J0 |
LPQPMPI |
7.36
|
-13.82 |
2.11 |
| P11171 |
TTEKSLV |
7.41
|
-13.81 |
2.12 |
| Q14155 |
PWSLSCL |
7.59
|
-12.99 |
2.94 |
|
DSKPAPL |
9.55
|
-11.47 |
4.46 |
|
TPKPWSL |
10.41
|
-12.60 |
3.33 |
| Q9UHC6 |
EPYNIDV |
5.31
|
-16.63 |
-0.70 |
|
TREPYNI |
8.18
|
-15.52 |
0.41 |
|
SPGYAKI |
8.90
|
-11.29 |
4.64 |
| P18827 |
GPSQADL |
7.22
|
-13.14 |
2.79 |
|
