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Matrix information:
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ADAN-name: 1KSW3.PDB
Scoring matrix: 1KSW3_mat
Uniprot code: P12931
Genome source: Homo sapiens
Wild-type ligand: KPQTQGLAKD
Foldx wt ligand score: 6.67
Foldx random average score for Homo sapiens: 10.776 Available information for P12931 in MINT (Nov 2008):
Nš of interacting proteins: 50
Proteins belonging to other specie: 11
Nš of interactions described: 106
Interactions with other species: 20
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48060
Total fragments: 22103987
Proteins after random average filtering: 48045
Total fragments: 11639522
Proteins after disorder filtering: 35197
Total fragments: 817509
Proteins after pattern filtering: 23686
Total fragments: 171124
Proteins after MINT filtering: 26
Total fragments: 311
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPQTQGLAKD |
6.67
|
-8.07 |
0.00 |
| Best peptides |
YPAMGGWWYC |
0.00
|
-9.27 |
-1.20 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13177 |
KPPAPPVRMS |
9.81
|
-10.24 |
-2.17 |
|
PPAPPVRMSS |
10.09
|
-8.16 |
-0.09 |
|
PAPPVRMSST |
10.62
|
-6.48 |
1.59 |
| Q8TBB1 |
RSNTPKPLHP |
10.64
|
-8.89 |
-0.82 |
| Q8WUM4 |
FPQPPQQSYY |
6.00
|
-11.30 |
-3.23 |
|
YPGYPGYCQM |
6.79
|
-8.21 |
-0.14 |
|
PTYPGYPGYC |
7.46
|
-9.05 |
-0.98 |
| Q16832 |
PVQPSGPEGV |
9.05
|
-4.49 |
3.58 |
|
KPVQPSGPEG |
10.11
|
-7.50 |
0.57 |
|
SEALPTSPMA |
10.44
|
-8.27 |
-0.20 |
| Q05193 |
PPVPSRPGAS |
8.27
|
-9.37 |
-1.30 |
|
VPSRPGASPD |
8.74
|
-8.05 |
0.02 |
|
PQVPSRPNRA |
8.85
|
-7.34 |
0.73 |
| P15941 |
SAPDNRPALG |
9.31
|
-7.86 |
0.21 |
|
PVTRPALGST |
10.23
|
-5.94 |
2.13 |
|
PATEPASGSA |
10.42
|
-4.18 |
3.89 |
| P09848 |
PDPATGPHAC |
8.87
|
-6.53 |
1.54 |
|
FPDPATGPHA |
9.31
|
-9.13 |
-1.06 |
| P00533 |
VPKRPAGSVQ |
8.13
|
-9.50 |
-1.43 |
|
PSCPNGSCWG |
8.50
|
-6.21 |
1.86 |
|
DPSCPNGSCW |
8.73
|
-7.27 |
0.80 |
| P49407 |
PPNLPCSVTL |
8.93
|
-9.18 |
-1.11 |
|
FEIPPNLPCS |
9.59
|
-9.51 |
-1.44 |
|
EIPPNLPCSV |
9.63
|
-7.99 |
0.08 |
| P22681 |
RPPKPFPRRI |
6.03
|
-10.12 |
-2.05 |
|
LPPVPSSRLG |
6.73
|
-9.87 |
-1.80 |
|
LPCTPGDCPS |
6.84
|
-9.29 |
-1.22 |
| P18031 |
PPRPPKRILE |
7.52
|
-10.43 |
-2.36 |
|
IPPPPRPPKR |
8.08
|
-10.98 |
-2.91 |
|
LSPEHGPVVV |
8.78
|
-6.92 |
1.15 |
| P03372 |
PPPQLSPFLQ |
8.02
|
-8.68 |
-0.61 |
|
LPYGPGSEAA |
8.07
|
-7.71 |
0.36 |
|
PYGPGSEAAA |
9.26
|
-6.39 |
1.68 |
| P49023 |
GPPKPGSQLD |
7.09
|
-8.27 |
-0.20 |
|
PPPPSSEALN |
8.20
|
-9.48 |
-1.41 |
|
VPPPPSSEAL |
8.34
|
-8.55 |
-0.48 |
| Q05397 |
RPGAPGHLGS |
6.31
|
-8.46 |
-0.39 |
|
PPRPGAPGHL |
7.81
|
-8.15 |
-0.08 |
|
KPPRPGAPGH |
8.34
|
-8.63 |
-0.56 |
| P50570 |
IPSRPGPQSV |
7.50
|
-8.40 |
-0.33 |
|
RGPTPGPPLI |
7.85
|
-8.80 |
-0.73 |
|
FPAPPQIPSR |
8.71
|
-9.31 |
-1.24 |
| Q07666 |
PPVPRGRGVG |
6.29
|
-9.07 |
-1.00 |
|
QPPLPHRSRG |
6.88
|
-10.48 |
-2.41 |
|
PPLPHRSRGG |
8.21
|
-7.38 |
0.69 |
| Q9C0H9 |
SPRSPGGRRG |
7.25
|
-7.61 |
0.46 |
|
PPSPPLNLHE |
7.66
|
-9.47 |
-1.40 |
|
PKAPHGQKAA |
7.66
|
-6.66 |
1.41 |
| P55196 |
LPPEKLPYLV |
5.67
|
-10.63 |
-2.56 |
|
SPQLPWAEYS |
6.44
|
-10.48 |
-2.41 |
|
PKKLPGDDRL |
6.84
|
-10.02 |
-1.95 |
| P00519 |
KPSQPGEGLK |
5.19
|
-9.39 |
-1.32 |
|
VPEMPHSKGQ |
6.14
|
-10.09 |
-2.02 |
|
SPLLPRKERG |
6.52
|
-9.20 |
-1.13 |
| Q9H5V8 |
MPRQPKKFQK |
7.11
|
-8.73 |
-0.66 |
|
PRQPKKFQKG |
8.07
|
-8.44 |
-0.37 |
|
TEMPRQPKKF |
8.63
|
-5.91 |
2.16 |
| Q13444 |
RPGPPQRALL |
6.13
|
-11.12 |
-3.05 |
|
LPSWPLPNIG |
7.00
|
-10.40 |
-2.33 |
|
KPLPADPQGR |
7.49
|
-8.19 |
-0.12 |
| Q06124 |
HGVPSDPGGV |
10.40
|
-5.78 |
2.29 |
|
PPCTPTPPCA |
10.67
|
-9.00 |
-0.93 |
| Q9Y5K6 |
RPKMPGRRLP |
5.90
|
-11.63 |
-3.56 |
|
PPPPPIAKIN |
8.25
|
-10.02 |
-1.95 |
|
KPPPPAKAPA |
8.50
|
-10.13 |
-2.06 |
| P56945 |
APAPPASQYT |
6.54
|
-9.96 |
-1.89 |
|
TPAQPQPGLH |
7.49
|
-8.93 |
-0.86 |
|
KDVPDGPLLR |
7.58
|
-9.11 |
-1.04 |
| P06241 |
PTPQHYPSFG |
10.09
|
-4.66 |
3.41 |
|
PQHYPSFGVT |
10.21
|
-7.41 |
0.66 |
|
DPTPQHYPSF |
10.69
|
-7.91 |
0.16 |
| P21860 |
VPIMPTAGTT |
8.09
|
-9.24 |
-1.17 |
|
PPHPPRPSSL |
9.02
|
-8.34 |
-0.27 |
|
HPVPIMPTAG |
9.50
|
-7.31 |
0.76 |
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