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Matrix information:
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ADAN-name: 1KA72.PDB
Scoring matrix: 1KA72_mat
Uniprot code: O60880
Genome source: Homo sapiens
Wild-type ligand: RKSLTIYAQVQK
Foldx wt ligand score: 8.98
Foldx random average score for Homo sapiens: 13.204 Available information for O60880 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 2
Nš of interactions described: 24
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18130296
Proteins after random average filtering: 40289
Total fragments: 10190095
Proteins after disorder filtering: 28884
Total fragments: 643012
Proteins after pattern filtering: 14505
Total fragments: 106512
Proteins after MINT filtering: 8
Total fragments: 95
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RKSLTIYAQVQK |
8.98
|
-3.08 |
0.00 |
| Best peptides |
RKyFyIDMyLWH |
0.00
|
2.54 |
5.62 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
PTTYQMDVNPEG |
7.79
|
-3.23 |
-0.15 |
|
NPDYQQDFFPKE |
8.67
|
-2.18 |
0.90 |
|
TCPPLMLYNPTT |
9.69
|
-1.88 |
1.20 |
| O15117 |
PKQLDMGDEVYD |
8.27
|
-4.10 |
-1.02 |
|
PPDDDIYDGIEE |
10.08
|
-1.11 |
1.97 |
|
QTSYSTTSLPPP |
11.01
|
-0.83 |
2.25 |
| Q9BZW8 |
QTFPGGGSTIYS |
12.78
|
1.24 |
4.32 |
| Q14155 |
PLTPAYHTLPHP |
9.73
|
-1.66 |
1.42 |
|
DSKPAPLTPAYH |
11.45
|
0.52 |
3.60 |
|
TPAYHTLPHPSH |
11.47
|
-0.92 |
2.16 |
| P21860 |
NGYVMPDTHLKG |
9.25
|
-3.45 |
-0.37 |
|
SGYMPMNQGNLG |
9.91
|
-3.17 |
-0.09 |
|
LEEEDVNGYVMP |
10.00
|
-5.86 |
-2.78 |
| P06239 |
LVTYEGSNPPAS |
12.28
|
-0.15 |
2.93 |
|
PLVTYEGSNPPA |
12.42
|
0.70 |
3.78 |
| Q16288 |
THYNNGNYTLIA |
10.28
|
-0.94 |
2.14 |
|
PTHYNNGNYTLI |
10.92
|
-1.61 |
1.47 |
|
YRLFNPSGNDFC |
12.98
|
-0.39 |
2.69 |
| P06241 |
SSGYRYGTDPTP |
8.92
|
-2.57 |
0.51 |
|
YPSFGVTSIPNY |
10.34
|
-0.54 |
2.54 |
|
GYRYGTDPTPQH |
10.86
|
-1.40 |
1.68 |
|
