ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1KA62.PDB
Scoring matrix: 1KA62_mat
Uniprot code: Q9NP31
Genome source: Homo sapiens
Wild-type ligand: RKSLTIyA
Foldx wt ligand score: 4.18
Foldx random average score for Homo sapiens: 10.382

Available information for Q9NP31 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
 Total fragments: 18291263
Proteins after random average filtering: 40308
 Total fragments: 9320382
Proteins after disorder filtering: 30269
 Total fragments: 765782
Proteins after pattern filtering: 14697
 Total fragments: 88849
Proteins after MINT filtering: 2
 Total fragments: 31


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RKSLTIyA

4.18

-5.96

0.00

Best peptides

RRSyDMyF

0.00

3.58

9.54

         
Interactors      
P00533

NPDYQQDF

5.65

-0.84

5.12

LDNPDYQQ

7.13

1.29

7.25

HPNCTYGC

7.37

0.00

5.96

P04626

DNLYYWDQ

6.80

-1.06

4.90

FDNLYYWD

8.53

0.57

6.53

YLTPQGGA

8.66

1.13

7.09

 


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