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Matrix information:
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ADAN-name: 1JYR2.PDB
Scoring matrix: 1JYR2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: APSyVNVQN
Foldx wt ligand score: 7.02
Foldx random average score for Homo sapiens: 20.045 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13547926
Proteins after random average filtering: 32209
Total fragments: 6699784
Proteins after disorder filtering: 23616
Total fragments: 440413
Proteins after pattern filtering: 11041
Total fragments: 60455
Proteins after MINT filtering: 8
Total fragments: 56
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
APSyVNVQN |
7.02
|
-18.80 |
0.00 |
| Best peptides |
HDDyyNKyp |
0.00
|
-20.67 |
-1.87 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
NGYNETTGE |
19.32
|
-4.42 |
14.38 |
| Q07889 |
KLPPKTYKR |
18.33
|
-5.65 |
13.15 |
|
KYSYPLKSP |
18.56
|
-4.17 |
14.63 |
|
LPPKTYKRE |
18.87
|
2.75 |
21.55 |
| Q07890 |
KLPPKTYKR |
18.33
|
-5.65 |
13.15 |
|
LPPKTYKRE |
18.87
|
2.75 |
21.55 |
| Q9UQC2 |
GDSEENYVP |
14.19
|
-8.83 |
9.97 |
|
TNSEDNYVP |
15.46
|
-7.40 |
11.40 |
|
YVPMQNPVS |
15.93
|
-10.02 |
8.78 |
| Q6S383 |
YSDPSTGEP |
19.37
|
-2.59 |
16.21 |
|
YYSPYSVSG |
19.68
|
-3.43 |
15.37 |
| Q13905 |
PSQYDNISG |
13.43
|
-9.38 |
9.42 |
|
HPSQYDNIS |
17.47
|
-4.71 |
14.09 |
|
QYDNISGED |
18.86
|
-5.50 |
13.30 |
| Q13480 |
HDSEENYVP |
13.09
|
-10.69 |
8.11 |
|
ELYVFNTPS |
14.88
|
-8.94 |
9.86 |
|
PPPYQLINV |
15.43
|
-9.99 |
8.81 |
| P58107 |
TGYPDPYGG |
19.48
|
-1.86 |
16.94 |
|
