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Matrix information:
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ADAN-name: 1JU53.PDB
Scoring matrix: 1JU53_mat
Uniprot code: P46108
Genome source: Homo sapiens
Wild-type ligand: GPRPPVPPSPAQ
Foldx wt ligand score: 3.85
Foldx random average score for Homo sapiens: 21.006 Available information for P46108 in MINT (Nov 2008):
Nš of interacting proteins: 13
Proteins belonging to other specie: 2
Nš of interactions described: 19
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18130120
Proteins after random average filtering: 40290
Total fragments: 11112622
Proteins after disorder filtering: 29751
Total fragments: 1296519
Proteins after pattern filtering: 21777
Total fragments: 445099
Proteins after MINT filtering: 11
Total fragments: 564
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
GPRPPVPPSPAQ |
3.85
|
-8.28 |
0.00 |
| Best peptides |
GANGGMPPMDHK |
0.00
|
-2.50 |
5.78 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P54253 |
TPQPGTPVSPVQ |
7.05
|
-6.62 |
1.66 |
|
PGNPGGRGHGGG |
8.41
|
-1.29 |
6.99 |
|
TGRTASPPAIPV |
9.33
|
-1.19 |
7.09 |
| P22681 |
RPIPKVPVSAPS |
7.12
|
-7.72 |
0.56 |
|
KPLPVPPTLRDL |
7.37
|
-7.43 |
0.85 |
|
EPRPDVPRLGST |
7.40
|
-10.55 |
-2.27 |
| P00533 |
APSRDPHYQDPH |
7.54
|
-4.22 |
4.06 |
|
NPAPSRDPHYQD |
8.36
|
-5.90 |
2.38 |
|
DPSCPNGSCWGA |
9.44
|
-7.27 |
1.01 |
| P49023 |
SPPGGPPKPGSQ |
7.45
|
-4.87 |
3.41 |
|
PPLPGALSPLYG |
8.43
|
-2.76 |
5.52 |
|
PGGPPKPGSQLD |
8.48
|
-2.74 |
5.54 |
| O00401 |
APSGPPPPPPSV |
3.86
|
-8.92 |
-0.64 |
|
RGRGAPPPPPSR |
4.27
|
-6.28 |
2.00 |
|
GPVAPPPPPPPP |
5.29
|
-8.01 |
0.27 |
| P15498 |
YGLPPPPGAIGP |
8.25
|
-3.11 |
5.17 |
|
LPPPPGAIGPFL |
10.41
|
0.79 |
9.07 |
|
PPPPGAIGPFLR |
10.72
|
-2.16 |
6.12 |
| P04626 |
GAAPQPHPPPAF |
5.81
|
-5.35 |
2.93 |
|
GGAAPQPHPPPA |
5.90
|
-3.86 |
4.42 |
|
APQPHPPPAFSP |
5.90
|
-8.42 |
-0.14 |
| P56945 |
GPGGPAQDIYQV |
4.70
|
-4.62 |
3.66 |
|
KPAGPGSGPPAT |
6.75
|
-2.63 |
5.65 |
|
AGPGSGPPATPA |
6.88
|
-0.18 |
8.10 |
| P21860 |
SGPGIAPGPEPH |
6.47
|
-0.17 |
8.11 |
|
HPVPIMPTAGTT |
7.53
|
-7.00 |
1.28 |
|
GPGIAPGPEPHG |
8.38
|
-5.83 |
2.45 |
| P84022 |
SPNPMSPAHNNL |
6.44
|
-5.81 |
2.47 |
|
AGSPNLSPNPMS |
7.66
|
-3.87 |
4.41 |
|
DAGSPNLSPNPM |
10.48
|
-3.46 |
4.82 |
| Q13905 |
LPLGGHPQPDGP |
5.19
|
-7.09 |
1.19 |
|
GPLAPGQQTDTP |
5.53
|
-3.14 |
5.14 |
|
GGHPQPDGPLAP |
5.87
|
-3.67 |
4.61 |
|
