ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1JEG2.PDB
Scoring matrix: 1JEG2_mat
Uniprot code: P41241
Genome source: Mus musculus
Wild-type ligand: IPPPLPERTPESFIVVEE
Foldx wt ligand score: 8.74
Foldx random average score for Mus musculus: 12.785

Available information for P41241 in MINT (Nov 2008):
Nš of interacting proteins: 1
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 6057
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 38389
 Total fragments: 17122385
Proteins after random average filtering: 38370
 Total fragments: 8988466
Proteins after disorder filtering: 19730
 Total fragments: 259941
Proteins after pattern filtering: 13124
 Total fragments: 88011
Proteins after MINT filtering: 1
 Total fragments: 9


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

IPPPLPERTPESFIVVEE

8.74

-6.91

0.00

Best peptides

EFDMFLKRTKGLDMIMDK

0.00

-3.77

3.14

         
Interactors      
O70469

PPHLPDPLYDSIQEDPGA

9.61

-6.14

0.77

PHDSLPSPSPGTLVPGMR

9.98

-6.10

0.81

LTGPPPHLPDPLYDSIQE

10.19

-8.31

-1.40

 


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