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Matrix information:
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ADAN-name: 1IO62.PDB
Scoring matrix: 1IO62_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: RHYRPLPPLP
Foldx wt ligand score: 8.15
Foldx random average score for Homo sapiens: 14.107 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13515704
Proteins after random average filtering: 32213
Total fragments: 7073303
Proteins after disorder filtering: 24116
Total fragments: 831783
Proteins after pattern filtering: 17213
Total fragments: 203179
Proteins after MINT filtering: 8
Total fragments: 257
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RHYRPLPPLP |
8.15
|
-0.52 |
0.00 |
| Best peptides |
RGGGFIGRLP |
0.00
|
5.72 |
6.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
PKPRPPRPLP |
9.42
|
0.62 |
1.14 |
|
RKKISPPTPK |
9.86
|
3.46 |
3.98 |
|
RPPRPLPVAP |
10.19
|
0.93 |
1.45 |
| Q07889 |
YPLKSPGVRP |
8.09
|
5.09 |
5.61 |
|
TSQHIPKLPP |
9.74
|
3.39 |
3.91 |
|
RRHLPSPPLT |
9.80
|
3.76 |
4.28 |
| Q9UKW4 |
PCPCVPKPVD |
12.86
|
5.16 |
5.68 |
| Q07890 |
PRQNSSPHLP |
7.97
|
1.38 |
1.90 |
|
SPRRRPGDPV |
8.46
|
5.98 |
6.50 |
|
FSLKSPGIRP |
8.69
|
5.20 |
5.72 |
| Q9UQC2 |
PRWGSPQQRP |
8.72
|
3.62 |
4.14 |
|
YIPMSPGAHH |
9.37
|
6.61 |
7.13 |
|
SAGHGPRSSP |
9.69
|
4.97 |
5.49 |
| Q13905 |
PFQLPLGGHP |
6.82
|
3.45 |
3.97 |
|
PFLGPPFQLP |
7.52
|
-0.14 |
0.38 |
|
GHPQPDGPLA |
8.47
|
5.90 |
6.42 |
| Q13480 |
PRTFPEGTLG |
9.47
|
6.33 |
6.85 |
|
GFRSSPKTPP |
9.71
|
2.31 |
2.83 |
|
SSPKTPPRRP |
10.59
|
3.09 |
3.61 |
| P58107 |
RGPREPGPAG |
6.63
|
4.77 |
5.29 |
|
PRGGEPQGPP |
7.90
|
3.87 |
4.39 |
|
LGAGTPPRPQ |
8.40
|
3.54 |
4.06 |
|
