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Matrix information:
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ADAN-name: 1H9O2.PDB
Scoring matrix: 1H9O2_mat
Uniprot code: P27986
Genome source: Homo sapiens
Wild-type ligand: yVPML
Foldx wt ligand score: 3.75
Foldx random average score for Homo sapiens: 13.485 Available information for P27986 in MINT (Nov 2008):
Nš of interacting proteins: 27
Proteins belonging to other specie: 5
Nš of interactions described: 83
Interactions with other species: 11
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48060
Total fragments: 22344072
Proteins after random average filtering: 48054
Total fragments: 10858522
Proteins after disorder filtering: 37321
Total fragments: 786083
Proteins after pattern filtering: 18289
Total fragments: 72695
Proteins after MINT filtering: 14
Total fragments: 125
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yVPML |
3.75
|
-12.91 |
0.00 |
| Best peptides |
yEWMN |
0.00
|
-11.08 |
1.83 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
LMLYN |
8.34
|
-4.31 |
8.60 |
|
MLYNP |
10.78
|
-5.08 |
7.83 |
|
TYQMD |
11.25
|
-7.10 |
5.81 |
| O15455 |
YLCNT |
12.04
|
-4.94 |
7.97 |
| P22681 |
TEYMT |
8.54
|
-6.94 |
5.97 |
|
DDGYD |
11.62
|
-1.28 |
11.63 |
|
YLFPD |
12.37
|
-4.98 |
7.93 |
| Q07666 |
PETYE |
10.70
|
-6.16 |
6.75 |
|
SEYYD |
10.76
|
-4.59 |
8.32 |
|
YYDYG |
11.85
|
-3.52 |
9.39 |
| P35568 |
YMMMS |
7.26
|
-9.71 |
3.20 |
|
YMPMS |
7.56
|
-9.79 |
3.12 |
|
YMNMS |
7.88
|
-8.54 |
4.37 |
| P42336 |
AMYVY |
10.36
|
-6.54 |
6.37 |
|
MYVYP |
11.87
|
-2.23 |
10.68 |
|
YVYPP |
13.31
|
-2.83 |
10.08 |
| Q9UQC2 |
YVPMN |
6.98
|
-10.71 |
2.20 |
|
YVPMQ |
7.38
|
-10.06 |
2.85 |
|
YIPMS |
8.36
|
-9.04 |
3.87 |
| P29353 |
HQYYN |
11.20
|
-5.80 |
7.11 |
|
YNDFP |
11.63
|
-6.75 |
6.16 |
| Q9Y5K6 |
SVYLS |
10.32
|
-6.11 |
6.80 |
|
YLSTP |
11.22
|
-6.63 |
6.28 |
|
DTCYS |
12.59
|
-0.45 |
12.46 |
| P43405 |
YDVVN |
9.97
|
-6.23 |
6.68 |
|
SYSFP |
13.05
|
-0.98 |
11.93 |
| P04626 |
PEYLT |
9.08
|
-6.54 |
6.37 |
|
PEYVN |
9.30
|
-6.12 |
6.79 |
|
NLYYW |
10.50
|
-2.01 |
10.90 |
| P21860 |
YEYMN |
5.48
|
-10.71 |
2.20 |
|
YMPMN |
5.89
|
-11.36 |
1.55 |
|
YMNRQ |
9.23
|
-9.52 |
3.39 |
| P06239 |
YEGSN |
10.41
|
-4.78 |
8.13 |
|
LVTYE |
11.33
|
-6.16 |
6.75 |
|
VTYEG |
12.16
|
-3.90 |
9.01 |
| Q13480 |
YVPMN |
6.98
|
-10.71 |
2.20 |
|
LYVFN |
10.08
|
-5.02 |
7.89 |
|
EENYV |
10.50
|
-6.10 |
6.81 |
|
