ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1GBR2.PDB
Scoring matrix: 1GBR2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: LLPKLPPK
Foldx wt ligand score: 5.52
Foldx random average score for Mus musculus: 5.793

Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
 Proteins belonging to other specie: 6
Nš of interactions described: 55
 Interactions with other species: 12

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 13502
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 30944
 Total fragments: 13452797
Proteins after random average filtering: 30942
 Total fragments: 6973386
Proteins after disorder filtering: 23012
 Total fragments: 672355
Proteins after pattern filtering: 14332
 Total fragments: 75819
Proteins after MINT filtering: 12
 Total fragments: 88


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

LLPKLPPK

5.52

-3.75

0.00

Best peptides

FMGVDMRH

0.00

3.40

7.15

         
Interactors      
Q62245

LKSPGVRP

3.30

-1.67

2.08

YSYPLKSP

4.33

-1.43

2.32

GVRPSNPR

5.12

0.97

4.72

P04925

WNKPSKPK

5.21

0.13

3.88

Q923U0

DLSPIVPV

4.67

-3.19

0.56

QISPNRPT

5.00

-1.46

2.29

PSAPSCDL

5.16

1.15

4.90

Q02384

LKSPGIRP

3.27

-1.67

2.08

SEEPLIPP

4.15

-1.63

2.12

DPLPDTPP

4.41

-0.29

3.46

Q91ZZ2

ASKPDGQP

3.19

1.00

4.75

PPLPGIRV

3.78

-0.90

2.85

PSSPASKP

4.12

0.34

4.09

Q60992

RGDPDSPW

2.86

-0.47

3.28

HGNPAPPG

4.22

0.41

4.16

PAPPGKPV

4.33

0.15

3.90

O35716

PAVPAPAP

4.51

0.49

4.24

SSSPAAPV

4.62

1.15

4.90

RPCPAVPA

5.69

0.87

4.62

Q80U87

EMAPSSAP

2.78

-1.90

1.85

LPTQMPPP

5.29

-1.69

2.06

PPEMAPSS

5.57

-0.03

3.72

Q9EQ32

ASAPGPPP

3.57

0.79

4.54

NLPPEISP

5.34

-2.58

1.17

PPPPDNEP

5.61

0.20

3.95

Q9Z1S8

PMNPGSST

0.80

-1.85

1.90

PMSPGPHH

1.28

-2.03

1.72

DFQPGSPS

3.35

-0.26

3.49

Q62077

DGPDGMPV

3.89

0.16

3.91

GPDGMPVI

5.35

-1.72

2.03

WDGPDGMP

5.57

0.86

4.61

Q9QYY0

PMTPGTFD

1.58

-1.78

1.97

PMNPNLSG

3.28

-2.02

1.73

PMNPNSPP

3.31

-2.47

1.28

 


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